Prevalence and correlation of Neisseria gonorroheae, Mycoplasma hominis and Ureaplasma urealyticum antibodies in unexplained infertile women having positive post coital test

Abstract

The probability that a vaginal infection can interfere with fertility is often overlooked. The microorganisms, their products may inhibit sperm morphol-ogy and motility. Abnormal cervical mucus and sperm interactions clarify infertility in 5% to 10% of couples with a fertility problem. The aim of this research study was to estimate the prevalence of Gonococcal (IgG), Myco-plasma hominis (IgG) and Ureaplasma urealyticum (T. mycoplasma) (IgG) antibodies in unexplained infertile women having positive post coital test (PCT). Blood samples of 50 positive PCT identified infertile females and 50 healthy pregnant females (age group of 24-36 yrs) were collected and ana-lyzed for Gonococcal (IgG), M. hominis (IgG) and T. mycoplasma (IgG) anti-bodies by ELISA technique. In the study group patients, only 12 % cases (6/ 50) were positive for IgG gonococcal antibodies but no any positive case was found in control group. 28% cases (14/50) were found positive for M. homi-nis IgG antibodies in study group patients and only 10 % cases (5/50) were positive in control group. Results statistically were insignificant. In case of T. mycoplasma IgG antibodies, 76% (38/50) infertile women were observed as positive while only 24% (12/50) cases of control group were found positive for the same (p < 0.001). The results were not significant for gonococcal and M. hominis antibodies but were highly significant for U. urealyticum IgG an-tibodies and it was concluded that it may be a cause of infertility in positive PCT cases as no any other known reason of infertility is noticed in such cases.