Prevalence and Clinical Utility of Human Papilloma Virus Genotyping in Patients with Cervical Lesions

Kaur, Parminder; Aggarwal, Aruna; Nagpal, Madhu; Oberoi, Loveena; Sharma, Swati

doi:10.1007/s13224-014-0508-5

Cited by 8 publications

(8 citation statements)

References 19 publications

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“…Type 16 was frequently the most common type encountered among the expatriates from Philippines, Arab, Indian subcontinent, and USA/Canada. [31][32][33][34][35] Among African patients, type 16 was not the commonest in present study unlike the previously available data, [36][37][38][39] commonest being type 51 in 3 patients, type 18 was not found and a few other types, 51 and 66, were noted. There was detection of a few Oncogenic HPV types which were not identified in the studies carried out in home country, [23][24][25][26] as highlighted in red in Table VIII, notably types 66,31,59,68 and 56 among Fili-pino expatriates.…”

Section: Resultscontrasting

confidence: 79%

“…20,[27][28][29][30] Among patients from Indian subcontinent, apart from 16 being commonest type, 66 and 35 which were not seen in previous studies, were observed. [31][32][33][34][35] Among African patients, type 16 was not the commonest in present study unlike the previously available data, [36][37][38][39] commonest being type 51 in 3 patients, type 18 was not found and a few other types, 51 and 66, were noted. Among patients of European origin, again type 16 was less common, 51 being the commonest, type 66 was seen unlike previous studies.…”

Section: Resultscontrasting

confidence: 79%

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Correlation of cervical cytology with high‐risk HPV molecular diagnosis, genotypes, and histopathology—A four year study from the UAE

Krishnan

Thomas

2015

Diagnostic Cytopathology

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Assessment of cervical cytology reporting pattern, correlation of cervical cytology with HPV molecular diagnosis, and biopsy histopathology is a useful way to audit our work and a good quality control practice. Higher prevalence of HPV HR types such as type 51, 31 as well as 66, 56, and 59 found in the present as well as many similar other studies apart from the commonest subtype 16 may imply necessity for development of more targeted and multivalent anti-HPV vaccines for protection of women in our region. HPV genotypes correlation with the nationalities of patients is useful from an epidemiological standpoint to plan preventive strategies.

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Section: Resultscontrasting

confidence: 79%

Section: Resultscontrasting

confidence: 79%

Correlation of cervical cytology with high‐risk HPV molecular diagnosis, genotypes, and histopathology—A four year study from the UAE

Krishnan

Thomas

2015

Diagnostic Cytopathology

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“…In part, this arises from the fact that they are constantly being exposed to a large number of risk factors facilitating the spread of sexually transmitted diseases [30]. Previous studies among the general population have reported that the prevalence of HPV ranged from 9% to 13% in the world [94]. As expected, our ndings indicated that the number of HPV-positive cases is signi cantly higher among FSWs compared to the general population, and the prevalence varied from 13% to 82% across the world.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Genotype Distribution of Genital Human Papillomavirus Infection in Female Sex Workers in the World: A Systematic Review and Meta-Analysis

Farahmand

Moghoofei

Dorost

et al. 2020

Preprint

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Background: Female sex workers (FSWs) are amongst the most susceptible groups to acquire human papillomavirus (HPV) infection and consequently, to develop cervical intraepithelial neoplasia and cervical cancer. This is the first systematic review and meta-analysis to provide estimates of the pooled prevalence of HPV infection and the distribution of HPV types among FSWs across the world. Methods: Five computerized databases were searched for relevant studies published since the inception date of databases to September 2019. The pooled HPV prevalence was calculated by the random effect model described by DerSimonian-Laird. Subgroup analysis was performed to identify the probable sources of heterogeneity. The meta-analysis was performed using the “Metaprop” function in the R package Meta. Results: Sixty-two studies involving 21402 FSWs from 33 countries were included in this meta-analysis, and the pooled HPV prevalence was 42.60% (95% confidence interval (CI): 38.58%-46.71%). HPV-16 (10.16%, 95% CI: 8.20%–12.51%), HPV-52 (7.98%, 95% CI: 5.91%–10.70%), and HPV-53 (6.01%, 95% CI: 4.40%–8.15%) were the most common high-risk HPV types identified among FSWs. The pooled estimated prevalence of HPV infection among FSWs before and after 2010 were slightly different, 43.64% (95% CI: 36.12%-51.46%) and 41.97% (95% CI: 37.28%-46.81%), respectively. Conclusion: Due to the high prevalence of HPV infection, particularly with high-risk types, FSWs have a great susceptibility to the development of cervical and vaginal cancers. Furthermore, they can transmit their infection to their clients, which may result in a high prevalence of HPV and the incidence of HPV-associated malignancies among the general population.

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“…In part, this arises from the fact that they are constantly being exposed to a large number of risk factors facilitating the spread of sexually transmitted diseases [83]. Previous studies among the general population have reported that the prevalence of HPV ranged from 9-13% in the world [84]. As expected, our findings indicated that the number of HPV-positive cases are significantly higher among FSWs compared to the general population, and the prevalence varied from 13-82% across the world.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Genotype Distribution of Genital Human Papillomavirus Infection in Female Sex Workers in the World: A Systematic Review and Meta-Analysis

Farahmand

Moghoofei

Monavari

et al. 2020

Preprint

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Background: Female sex workers (FSWs) are amongst the most susceptible groups to acquire human papillomavirus (HPV) infection and consequently, to develop cervical intraepithelial neoplasia and cervical cancer. This is the first systematic review and meta-analysis to provide estimates of the pooled prevalence of HPV infection and distribution of HPV types among FSWs across the world. Methods: Five computerized databases were searched for relevant studies published since the inception date of databases to September 2019. The pooled HPV prevalence was calculated by the random effect model described by DerSimonian-Laird. Subgroup analysis was performed to identify the probable sources of heterogeneity. The meta-analysis was performed using the “Metaprop” function in the R package Meta. Results: Sixty-six studies involving 22938 FSWs from 34 countries were included in this meta-analysis, and the pooled HPV prevalence was 41.97% (95% confidence interval (CI): 37.99%-46.05%). HPV-16 (10.42%, 95% CI: 8.61%–12.55%), HPV-52 (7.76%, 95% CI: 5.75%–10.39%), and HPV-53 (6.09%, 95% CI: 4.55%–8.12%) were the most common high-risk HPV types identified among FSWs. The polled estimated prevalence of HPV infection among FSWs before and after 2010 were slightly different, 43.64% (95% CI: 36.12%-51.46%) and 41.01% (95% CI: 36.35%-45.83%), respectively. Conclusion: Due to the high prevalence of HPV infection, particularly with high-risk types, FSWs have a great susceptibility to the development of cervical and vaginal cancers. Furthermore, they can transmit their infection to their clients, which may result in a high prevalence of HPV and incidence of HPV-associated malignancies among the general population.

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Prevalence and Clinical Utility of Human Papilloma Virus Genotyping in Patients with Cervical Lesions

Abstract: Our study generates data of HPV prevalence in patients with cervical lesions visiting tertiary care institute. The data generated will be useful for laying guidelines for mass screening of HPV detection, treatment, and prophylaxis.

Cited by 8 publications

References 19 publications

Correlation of cervical cytology with high‐risk HPV molecular diagnosis, genotypes, and histopathology—A four year study from the UAE

Correlation of cervical cytology with high‐risk HPV molecular diagnosis, genotypes, and histopathology—A four year study from the UAE

Prevalence and Genotype Distribution of Genital Human Papillomavirus Infection in Female Sex Workers in the World: A Systematic Review and Meta-Analysis

Prevalence and Genotype Distribution of Genital Human Papillomavirus Infection in Female Sex Workers in the World: A Systematic Review and Meta-Analysis

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