Prevalence and characteristics of psoriatic arthritis in Chinese patients with psoriasis

Yang, Qing; Qu, Lujiang; Tian, Haijun; Hu, Yingguo; Peng, J; Yu, Xianpeng; Yu, Chang‐Ping; Pei, Zhenhuan; Wang, G.; Shi, Bin; Zhang, F.; Zhang, Y.

doi:10.1111/j.1468-3083.2011.03985.x

Cited by 110 publications

(136 citation statements)

References 26 publications

(43 reference statements)

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“…The reported prevalence of nail changes in PsA varied from 32 to 97 % [7] Similarly, the frequency of DIP arthritis was highly variable in different research, from 5.4 to 89 % [2,11,18]. A local analysis reported 89 % of 127 PsA patients had peripheral arthritis; unfortunately, joint area involved was not described [2].…”

Section: Discussionmentioning

confidence: 99%

Psoriatic nail involvement and its relationship with distal interphalangeal joint disease

et al. 2016

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Psoriatic nail disease and distal interphalangeal (DIP) arthritis both are common manifestations of psoriatic arthritis (PsA). Several clinical characteristics are allegedly associated with DIP joint damage, particularly nail psoriasis. However, there is little evidence to substantiate this phenomenon. The purpose of this study is to investigate the relationship between DIP involvement, nail psoriasis and other parameters. A cross-sectional study involved 45 patients from local rheumatology clinic. Four hundred fifty psoriatic fingernails scored, and the radiographs of all these fingers were reviewed to define PsA DIP arthritic changes. 64.4 % patients had nail psoriasis and 35.6 % had DIP arthritis. Univariate analysis identified that swollen joint-count, digits with chronic dactylitis, HLA-B27 status and nail psoriasis were associated with DIP arthritis. Regression model supported that nail disease was the most significant associated factor of DIP arthritis (OR 9.7, p = 0.05). Nail psoriasis was identified in 40.2 % of digits. Pitting (29.6 %), onycholysis (15.1 %), crumbling (8.2 %), nail bed hyperkeratosis (2.0 %) were noted with the mean modified Nail Psoriasis Severity Index of 0.95 +/-1.68. Among all digits, 57 had DIP arthritis while 393 did not. Within DIP joints with PsA radiological change, 59.6 % had nail disease. Chi-square test with the Bonferroni correction further supported an association between nail psoriasis and DIP involvement with p value of 0.001. Two specific nail subtypes-crumbling and onycholysis-were found to be significantly associated with DIP disease. A significant proportion of PsA patients had nail involvement and DIP arthritis. PsA patients with nail changes may be more susceptible to DIP disease.

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Section: Discussionmentioning

confidence: 99%

Psoriatic nail involvement and its relationship with distal interphalangeal joint disease

et al. 2016

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“…Ultrasound enthesopathy was present in 11.6 % of entheses in the psoriasis group and 5.3% of entheses in the control group. Similarly, Yang Q [20] found that oligoarthritis (48.2 %) was the most common manifestation pattern, followed by enthesitis (26.8 %), spondylitis (26.8 %), polyarthritis (19.6 %) and classic DIP arthritis (5.4 %).…”

Section: Discussionmentioning

confidence: 99%

“…Frediani B [31] demonstrated that PsA is associated with psoriatic lesions of the skin and/or nails, and serological tests for rheumatoid arthritis are negative. Yang Q et al [20] compared patients with PsA and patients without PsA, patients with PsA had more severe skin disease (mean PASI 9.7 vs. 6.0), higher frequency of nail changes (46.4 % vs. 21.0 %) and scalp involvement (90.2 % vs. 76.4 %). Also, Reich K et al [28] compared patients with arthritis and patients without arthritis, patients with PsA had more severe skin symptoms (mean PASI 14.3 vs. 11.5).…”

Section: Discussionmentioning

confidence: 99%

Enthesopathy and the Cutaneous Disease Activities in Psoriatic Arthritis

et al. 2013

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Aim: To investigate entheseal abnormalities by using Leeds Enthesitis Index (LEI) score in Psoriatic arthritis (PsA). Also, to find the correlation of LEI score and parameters of the activities of the cutaneous disease at baseline and after 6 months of treatment in PsA. Furthermore, to find correlation between LEI score and C-reactive protein (CRP) and Psoriasis Area and Severity Index (PASI) score as well as acute phase reactants. Materials and Methods:A total of thirty-nine patients with PsA and thirty-five age and sex matched healthy subjects were recruited. Clinical and laboratory assessment of disease activity included LEI score, PASI score, erythrocyte sedimentation rate (ESR) and CRP and were measured at baseline and after 6 months of treatment.Results: Enthesopathy showed a significant prevalence among PsA of 20.5%. We found a highly significant decreased in LEI score, PASI score, ESR and CRP at baseline compared to results after 6 months of treatment in PsA. A significant correlation between PASI score and LEI score was found. Also, PASI score was significant correlated with ESR and CRP in PsA. Conclusion:Enthesopathy showed a significant prevalence among PsA. The good potential parameters for PsA were LEI score, PASI score, ESR and CRP in PsA. Also, they may be the predictive value of changes induced by biological treatment in PsA.

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“…В ходе программы по псо-риатическому артриту Торонтского университета было показано, что энтезит присутствовал у 14,8 % пациентов при поступлении и у 35,9 % больных в течение периода наблюдения. У представителей неевропейского населе-ния частота клинических случаев энтезита колеблется от 7,8 % (в Индии) до 27 % (в Бразилии [65] и Китае [66]). При псориатическом СА частота случаев энтезита соста-вила 10 %, вне зависимости от стадии заболевания: ран-ней (<2 лет) или поздней (>10 лет).…”

Section: энтезит у пациентов с паunclassified

Enthesitis and Psoriatic Onychopathy as a Factor for Prediction of Psoriatic Arthritis in Psoriasis

Сидорчик

Линев

Радзыня

et al. 2018

Vestnik dermatologii i venerologii

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Psoriatic arthritis is a psoriasis-related spondyloarthropathy that occurs in 20–30 % of patients with psoriasis. Psoriatic arthritis affects the patient’s quality of life indicators and are more often associated with disabilities of working age than psoriasis skin form. Nail psoriasis has been proposed as a predictor for the development of psoriatic arthritis. The inflammation involving the entheses, called enthesitis, is an early inflammatory change seen in psoriatic arthritis, and nail changes appear to result from the close relationship between the nail and the enthesis of the distal interphalangeal extensor tendon, one of the main entheseal compartments affected in psoriatic arthritis. Various imaging studies have demonstrated that there is a considerable proportion of undiagnosed psoriatic arthritis among patients with psoriasis. Since early detection and treatment of psoriatic arthritis could, ultimately, allow the prevention of clinical and radiologic progression of the disease, there is the need to establish clinical indicators to detect this risk.

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Prevalence and characteristics of psoriatic arthritis in Chinese patients with psoriasis

Cited by 110 publications

References 26 publications

Psoriatic nail involvement and its relationship with distal interphalangeal joint disease

Psoriatic nail involvement and its relationship with distal interphalangeal joint disease

Enthesopathy and the Cutaneous Disease Activities in Psoriatic Arthritis

Enthesitis and Psoriatic Onychopathy as a Factor for Prediction of Psoriatic Arthritis in Psoriasis

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