Prevalence and characteristics of Becker nevus in Brazilian 18‐year‐old males

Almeida, Hiram Larangeira de; Duquia, Rodrigo Pereira; Souza, Paulo Ricardo Martins; Breunig, Juliano de Avelar

doi:10.1111/j.1365-4632.2009.04224.x

Cited by 12 publications

(11 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…BN lesions usually appeared on the upper trunk and upper limbs in this series, especially on scapular region, while the frequency of lower limb involvement was higher than the previous reports (21.7% vs. 3.2%~12.8%)47. This discrepancy may be due to the case recruitment and misdiagnosis and/or undiagnosis of atypical cases.…”

Section: Discussioncontrasting

confidence: 76%

Clinicopathological Features and Immunohistochemical Alterations of Keratinocyte Proliferation, Melanocyte Density, Smooth Muscle Hyperplasia and Nerve Fiber Distribution in Becker's Nevus

et al. 2016

View full text Add to dashboard Cite

BackgroundAlthough Becker's nevus (BN) is a relatively common disease, the systematic studies of clinicopathological and immunohistochemical results are poorly reported.ObjectiveTo investigate the clinicopathological features and immunohistochemical alterations of keratinocyte proliferation, melanocyte density, smooth muscle hyperplasia and nerve fiber distribution in BN.MethodsClinical and pathological data were collected in 60 newly-diagnosed BN cases. Immunohistochemical stain of Ki-67, Melan-A, keratin 15, smooth muscle actin and protein gene product 9.5 was performed in 21 cases.ResultsThe median diagnostic and onset age was 17 and 12 years, respectively. Skin lesions usually appeared on the upper trunk and upper limbs. The pathological features included the rete ridge elongation and fusion and basal hyperpigmentation. Epidermal Ki-67, Melan-A and keratin 15 expression and dermal nerve fiber length were significantly higher in lesional and perilesional skin than in normal skin (p<0.05~0.01), while smooth muscle actin expression was upregulated only in skin lesion (p<0.05).ConclusionAlthough the clinical diagnosis of BN is often straightforward, histopathology is helpful to differentiate from other pigmentary disorders. The hyperproliferation of keratinocytes, melanocytes, arrector pili muscle and dermal nerve fibers could be involved in the pathogenesis of BN.

show abstract

Section: Discussioncontrasting

confidence: 76%

Clinicopathological Features and Immunohistochemical Alterations of Keratinocyte Proliferation, Melanocyte Density, Smooth Muscle Hyperplasia and Nerve Fiber Distribution in Becker's Nevus

et al. 2016

View full text Add to dashboard Cite

show abstract

“…An interesting observation arising from our study is the presence of hypertrichosis on the surface of BN in only 37 cases, 21 of whom were aged 11 and older; hair growth on BN was seen after puberty. Terminal hairs was observed on the BN of 70% of young Italian men (1) but only in 23.1% of Brazilian teenagers (8). This difference may be because of the age of our patients, because androgenic stimulation seems to have an important role in body hair development during adolescence, when the most prominent hormone changes occur (5,7,8).…”

Section: Discussionmentioning

confidence: 99%

“…Terminal hairs was observed on the BN of 70% of young Italian men (1) but only in 23.1% of Brazilian teenagers (8). This difference may be because of the age of our patients, because androgenic stimulation seems to have an important role in body hair development during adolescence, when the most prominent hormone changes occur (5,7,8). The androgenic etiopathogenic role in the classically described mixed form oft BN (hairy and hyperpigmented) may explain the higher prevalence of BN diagnosed in men.…”

Section: Discussionmentioning

confidence: 99%

Clinical Characteristics of Becker’s Nevus in Children: Report of 118 Cases from Italy

Patrizi

Medri

Raone

et al. 2012

Pediatric Dermatology

View full text Add to dashboard Cite

We performed a retrospective study covering a 10-year period (January 1997-January 2007) on children referred to our unit or followed up for Becker's nevus (BN). The aim of this study was to better define the characteristics of BN in childhood, when this hypermelanosis is more frequent than the limited number of studies might suggest. Our data show that BN in children has predilection sites similar to those in adults, but hypertrichosis is rarer. Sun exposure does not appear to play an etiopathogenetic role. The higher incidence in men reported in adult case studies was not found in children. During and after puberty, androgenic stimulation is known to play a pathogenetic role in BN, especially in men, but our cases were mostly younger than 6 years old.

show abstract

“…To date, very few studies have evaluated the prevalence of BN in a general population which ranged (0.25-4.19%). (4,(8)(9)(10)(11) Although the etiopathogenesis of BN remains unclear, it has been hypothesized that androgen may play a role. A segmented increase in androgen receptors and probable heightened sensitivity to androgen have been postulated.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Clinical Characteristics of Becker’s Nevi in Young Jordanian Males

Tawara¹,

Qa’qaa²

2013

JRMS

View full text Add to dashboard Cite

Objective: The aim of this study is to determine the prevalence of Becker's nevus among young men in Jordan and to define its clinical characteristics. Method: We conducted a survey of all consecutive young male patients who were attending an entry medical examination for Mu'tah Military University in the years 2008 and 2012. The candidates underwent complete physical examination of the skin and the following demographic features were analyzed: age, skin phototype, district of origin, sun exposure, onset, awareness of lesion(s), site, size, hypertrichosis, and other associated features. Results: A sample of 9.862 teenager-males, aged 18-20 years, were examined. There were 642 Becker's nevus cases diagnosed, with a prevalence of 6.5%. Only 8.1% admitted onset during preschool age. About 59.8% had onset during 12-15 years old, 13.4% during 15-20 years, and 13.1% during 6-12 years. In 36 cases (5.6%), the patient could not determine age of onset. A unilateral distribution was observed in all candidates. Upper chest and shoulders were involved in 68.3%, followed by arms (13.1%), lower trunk (8.8%), lower extremities (7.6%), forearms (1.7%), and head and neck (1.4%). Seven cases (1.1%) had Blaschkoid lines distribution. Lesional hypertrichosis was clinically evident in 484 Becker's nevi (75.4%). Candidates with origin from north of Jordan had the highest prevalence. Seven cases showed associated features consistent with Becker's nevus syndrome. Conclusion: We believe that Becker's nevus is under-reported and has an earlier age of onset than it was believed. Our study showed a notably higher prevalence of Becker's nevus than it has been reported before. Becker's nevus syndrome should be always considered and searched for when examining patients with Becker's nevus.

show abstract

Prevalence and characteristics of Becker nevus in Brazilian 18‐year‐old males

Cited by 12 publications

References 6 publications

Clinicopathological Features and Immunohistochemical Alterations of Keratinocyte Proliferation, Melanocyte Density, Smooth Muscle Hyperplasia and Nerve Fiber Distribution in Becker's Nevus

Clinicopathological Features and Immunohistochemical Alterations of Keratinocyte Proliferation, Melanocyte Density, Smooth Muscle Hyperplasia and Nerve Fiber Distribution in Becker's Nevus

Clinical Characteristics of Becker’s Nevus in Children: Report of 118 Cases from Italy

Prevalence and Clinical Characteristics of Becker’s Nevi in Young Jordanian Males

Contact Info

Product

Resources

About