Pretreatment of flaxseed protein isolate by high hydrostatic pressure: Impacts on protein structure, enzymatic hydrolysis and final hydrolysate antioxidant capacities

Perreault, Véronique; Hénaux, Loïc; Bazinet, Laurent; Doyen, Alain

doi:10.1016/j.foodchem.2016.10.100

Cited by 67 publications

(41 citation statements)

References 39 publications

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“…Within the animal kingdom, HHPassisted enzymatic hydrolysis has been applied to whey protein isolate [99] and betalactoglobulin [100] to release bioactive peptides. Similarly, this technology has been employed to produce bioactive hydrolyzates from pinto beans [101], kidney beans [102], soy protein [103], and flaxseed protein [104].…”

Section: Release Of Bioactive Peptidesmentioning

confidence: 99%

A Review on the Extraction and Processing of Natural Source-Derived Proteins through Eco-Innovative Approaches

2021

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In addition to their nutritional and physiological role, proteins are recognized as the major compounds responsible for the rheological properties of food products and their stability during manufacture and storage. Furthermore, proteins have been shown to be source of bioactive peptides able to exert beneficial effects on human health. In recent years, scholarly interest has focused on the incorporation of high-quality proteins into the diet. This fact, together with the new trends of consumers directed to avoid the intake of animal proteins, has boosted the search for novel and sustainable protein sources and the development of suitable, cost-affordable, and environmentally friendly technologies to extract high concentrations of valuable proteins incorporated into food products and supplements. In this review, current data on emergent and promising methodologies applied for the extraction of proteins from natural sources are summarized. Moreover, the advantages and disadvantages of these novel methods, compared with conventional methods, are detailed. Additionally, this work describes the combination of these technologies with the enzymatic hydrolysis of extracted proteins as a powerful strategy for releasing bioactive peptides.

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Section: Release Of Bioactive Peptidesmentioning

confidence: 99%

A Review on the Extraction and Processing of Natural Source-Derived Proteins through Eco-Innovative Approaches

2021

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“…Under this pressure, the primary structures of proteins can remain intact. When the HHP is >400 MPa, the protein is rapidly denatured (67). HHP transforms the conformation of phospholipid bilayers from fluid-crystalline type to gel-like type (68).…”

Section: Effects Of High Hydrostatic Pressure On Biomacromoleculesmentioning

confidence: 99%

“…HHP is known to denature proteins and it does not affect covalent bonds, which signifies that the primary and secondary structures of proteins are preserved while the tertiary and quaternary structures are changed (73). Perreault et al indicated that for some types of proteins there may be a partial or complete loss of efficiency after HHP treatment (67). HHP disrupts non-covalent chemical bonds, which are essential for maintaining the structure and function of proteins.…”

Section: Effects Of High Hydrostatic Pressure On Proteinmentioning

confidence: 99%

Research and application of hydrostatic high pressure in tumor vaccines (Review)

Yan

Lin

et al. 2021

Oncol Rep

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It is well known that hydrostatic pressure (HP) is a physical parameter that is now regarded as an important variable for life. High hydrostatic pressure (HHP) technology has influenced biological systems for more than 100 years. Food and bioscience researchers have shown great interest in HHP technology over the past few decades. The development of knowledge related to this area can better facilitate the application of HHP in the life sciences. Furthermore, new applications for HHP may come from these current studies, particularly in tumor vaccines. Currently, cancer recurrence and metastasis continue to pose a serious threat to human health. The limited efficacy of conventional treatments has led to the need for breakthroughs in immunotherapy and other related areas. Research into tumor vaccines is providing new insights for cancer treatment. The purpose of this review is to present the main findings reported thus far in the relevant scientific literature, focusing on knowledge related to HHP technology and tumor vaccines, and to demonstrate the potential of applying HHP technology to tumor vaccine development.

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“…Lately, scientists have been testing enzymatic hydrolysis carried out after or during the application of non-thermal techniques, such as high pressure, ultrasound or microwave. The global conclusions are that high hydrostatic pressure and ultrasound pre-treatment improve the efficacy of enzymatic hydrolysis and the consequent release of bioactive peptides [60][61][62][63]. Regarding the protein structure, the tertiary and quaternary structures are generally affected by high-pressure treatment, while the secondary structures tend to be maintained.…”

Section: Enzymatic Hydrolysis Reactionmentioning

confidence: 99%

Antidiabetic Food-Derived Peptides for Functional Feeding: Production, Functionality and In Vivo Evidences

Rivero‐Pino

Espejo-Carpio

Guadix

2020

Foods

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Bioactive peptides released from the enzymatic hydrolysis of food proteins are currently a trending topic in the scientific community. Their potential as antidiabetic agents, by regulating the glycemic index, and thus to be employed in food formulation, is one of the most important functions of these peptides. In this review, we aimed to summarize the whole process that must be considered when talking about including these molecules as a bioactive ingredient. In this regard, at first, the production, purification and identification of bioactive peptides is summed up. The detailed metabolic pathways described included carbohydrate hydrolases (glucosidase and amylase) and dipeptidyl-peptidase IV inhibition, due to their importance in the food-derived peptides research field. Then, their characterization, concerning bioavailability in vitro and in situ, stability and functionality in food matrices, and ultimately, the in vivo evidence (from invertebrate animals to humans), was described. The future applicability that these molecules have due to their biological potential as functional ingredients makes them an important field of research, which could help the world population avoid suffering from several diseases, such as diabetes.

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Pretreatment of flaxseed protein isolate by high hydrostatic pressure: Impacts on protein structure, enzymatic hydrolysis and final hydrolysate antioxidant capacities

Cited by 67 publications

References 39 publications

A Review on the Extraction and Processing of Natural Source-Derived Proteins through Eco-Innovative Approaches

A Review on the Extraction and Processing of Natural Source-Derived Proteins through Eco-Innovative Approaches

Research and application of hydrostatic high pressure in tumor vaccines (Review)

Antidiabetic Food-Derived Peptides for Functional Feeding: Production, Functionality and In Vivo Evidences

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