Presynchronization strategy using prostaglandin F2α, gonadotropin-releasing hormone, and detection of estrus to improve fertility in a resynchronization program for dairy cows

Mendonça, L.G.D.; Rocha, L.; Voelz, B.E.; Lima, G.T.; Scanavez, A.L.A.; Stevenson, Jeffrey S.

doi:10.1016/j.theriogenology.2018.09.027

Cited by 9 publications

(13 citation statements)

References 26 publications

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“…The proportion of cows bearing a CL at 32 ± 3 d after AI in the AIER treatment was in the lower end of the expected range for nonpregnant previously inseminated lactating dairy cows (Wijma et al, 2017;Wijma et al, 2018). Nevertheless, our observations are still in agreement with previous studies that evaluated CL presence at this stage after AI (Giordano et al, 2015;Mendonça et al, 2019). Collectively, for the AIER treatment the relatively low proportion of CL cows, and the fact that 52% were not AIE after the PGF 2α treatment resulted in only 27% of cows reinseminated before 42 ± 3 d after AI (i.e., 10 d after FTI).…”

Section: Discussionsupporting

confidence: 91%

“…Various strategies have been evaluated to maximize the number of cows inseminated upon detection of estrus for second and greater AI services (McArt et al, 2010;Bruno et al, 2013;Chebel et al, 2013;Giordano et al, 2015;Mendonça et al, 2019). However, only a limited number of experiments reported time to pregnancy in cows that remained in the same management strategy from immediately after first service up to the end of the insemination period.…”

Section: Discussionmentioning

confidence: 99%

“…In recent years, research has been done on development of reproductive management programs for second and subsequent AI services that promote AIE (hereafter AIE-type strategy) after induction of estrus rather than blanket use of TAI for cows not reinseminated at spontaneous estrus (McArt et al, 2010;Bruno et al, 2013;Chebel et al, 2013;Giordano et al, 2015;Mendonça et al, 2019). These strategies could be beneficial for farms that strive to maximize reinsemination of cows upon detected estrus.…”

Section: Introductionmentioning

confidence: 99%

“…These strategies could be beneficial for farms that strive to maximize reinsemination of cows upon detected estrus. Programs designed to promote AIE usually include treatment with PGF 2α to promote expression of estrus in all nonpregnant cows (Bruno et al, 2013;Chebel et al, 2013;Mendonça et al, 2019) or only cows with a corpus luteum (CL;McArt et al, 2010;Giordano et al, 2015). In the latter type of program, cows that do not receive PGF 2α may receive a TAI protocol aimed at improving P/AI of cows without a functional CL (Giordano et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

A reproductive management program aimed at increasing reinsemination of nonpregnant dairy cows at detected estrus resulted in similar reproductive performance to a program that favored timed artificial insemination

Masello

Cegłowski

Thomas

et al. 2020

Journal of Dairy Science

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The objective of this experiment was to compare time to pregnancy and proportion of cows not pregnant 210 d after first service for cows managed for second and subsequent artificial insemination (AI) services with a reproductive management program that promoted reinsemination at detected estrus (AIE) or a program that promoted timed AI (TAI). After first service, lactating Holstein cows were blocked by parity and randomly assigned to d 32 Resynch (D32R; n = 464) or AIE Resynch (AIER; n = 512). To determine the effect of management strategies on time to pregnancy and cows not pregnant by the end of a 210 d at-risk period after first AI service, cows remained in AIER and D32R until pregnancy or herd exit. Cows in D32R received a GnRH treatment 32 ± 3 d after AI (first treatment intervention; FTI). Nonpregnancy diagnosis was conducted 7 d later by transrectal ultrasonography when nonpregnant cows with a corpus luteum (CL) ≥15 mm completed the Resynch protocol (PGF 2α , 56 h later GnRH, and 16 to 18 h later TAI) and cows without a CL (NoCL cows) were enrolled in a PreG-Ovsynch protocol (GnRH, 7 d later GnRH, 7 d later PGF 2α , 56 h later GnRH, and 16 to 18 h TAI) to receive TAI. For the AIER treatment, nonpregnant cows with a CL ≥15 mm observed by transrectal ultrasonography 32 ± 3 d after AI (i.e., FTI) received PGF 2α to induce estrus. Cows not AIE within 7 d were enrolled in Resynch (GnRH, 7 d later PGF 2α , 56 h later GnRH, and 16 to 18 h TAI). Cows in the NoCL group in AIER were enrolled in PreG-Ovsynch. Detection of estrus was performed based on visual observation of behavioral signs of estrus and tail-paint removal. Binomial data were analyzed with logistic regression and time to event data with Cox's proportional regression. After the FTI, a greater proportion of cows were AIE in AIER than D32R (36.0 vs. 11.9%) and more cows were AIE within 7 d of the FTI for AIER (25.0%) than D32R (4.8%). Overall pregnancy per AI at 68 ± 3 d after AI did not differ (AIER = 35.5% vs. D32R = 34.7%). The hazard of pregnancy up to 210 d after first AI for all cows enrolled (hazard ratio = 1.04, 95% CI 0.90 to 1.19) and for cows that received treatments only (D32R = 308, AIER = 349; hazard ratio = 1.00, 95% CI 0.85 to 1.19) did not differ. We conclude that a program aimed at increasing the proportion of cows reinseminated at detected estrus by treatment with PGF 2α at 32 ± 3 d after AI may be an alternative strategy for dairy farms that prefer or need to inseminate more cows at detected estrus rather than by TAI.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A reproductive management program aimed at increasing reinsemination of nonpregnant dairy cows at detected estrus resulted in similar reproductive performance to a program that favored timed artificial insemination

Masello

Cegłowski

Thomas

et al. 2020

Journal of Dairy Science

View full text Add to dashboard Cite

show abstract

“…As an example, PGF2a is used in fertilization procedures, in addition to GnRH, to pre-synchronize ovulation before applying for a resynchronization program in cows in dairy herds with acceptable pregnancy outcomes (149).…”

Section: Prostaglandins In Implantation and Maintenance Of Gestationmentioning

confidence: 99%

Molecules and Prostaglandins Related to Embryo Tolerance

et al. 2020

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Effect of progesterone supplementation in a resynchronization protocol on follicular dynamics and pregnancy success

et al. 2020

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Presynchronization strategy using prostaglandin F2α, gonadotropin-releasing hormone, and detection of estrus to improve fertility in a resynchronization program for dairy cows

Cited by 9 publications

References 26 publications

A reproductive management program aimed at increasing reinsemination of nonpregnant dairy cows at detected estrus resulted in similar reproductive performance to a program that favored timed artificial insemination

A reproductive management program aimed at increasing reinsemination of nonpregnant dairy cows at detected estrus resulted in similar reproductive performance to a program that favored timed artificial insemination

Molecules and Prostaglandins Related to Embryo Tolerance

Effect of progesterone supplementation in a resynchronization protocol on follicular dynamics and pregnancy success

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