Presurgical finite element simulation of scoliosis correction

Subbaraj, K.; Ghista, Dhanjoo N.; Viviani, G R

doi:10.1016/0141-5425(89)90159-3

Cited by 13 publications

(6 citation statements)

References 6 publications

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“…A finite element analysis (FEA) of the spine deformity correction has made an important contribution to our understanding of the biomechanical behavior of the human scoliotic spine and its mechanisms [6]. Subbaraj et al created a presurgical spine Finite Element Model (FEM) to simulate the Luque system (Luque rods), which demonstrates comparable results to post-surgical scoliosis correction procedure [7]. Based on the Hueter-Volkman law for bone growth modulation, recent research approaches have utilized FEA in order to simulate the progression of non-instrumented idiopathic scoliosis [8][9][10].…”

Section: Iintroductionmentioning

confidence: 99%

Finite element simulation of a scoliotic spine with periodic adjustments of an attached growing rod

Abolaeha

Weber

Ross³

2012

2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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Early Onset Scoliosis (EOS) is a deformity of spine which occurs during growth. Spinal growing rod instrumentation is currently a procedure of early onset scoliosis management and newer technologies to treat scoliosis without fusion hold the exciting promise of a new paradigm in spinal deformity care. A Finite Element Model (FEM) of a scoliotic spine was created and enhanced to simulate spine growth after the attachment of a growing rod. Growing rod instrumentation was included utilizing FEA to accurately simulate the required 3D forces and moments to achieve the desired correction. We measured forces on the rods and the spine during adjustment periods (for correction of the spinal deformity) and during growth periods. For this study, a two-year period was simulated with adjustments at six month intervals. The FEM allowed us to collect data during growth periods from sensors which are only accessible during the surgical procedures.

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Section: Iintroductionmentioning

confidence: 99%

Finite element simulation of a scoliotic spine with periodic adjustments of an attached growing rod

Abolaeha

Weber

Ross³

2012

2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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“…In the past many of these models have been developed, varying from very detailed micro models10 for close studies of the mechanical behavior on motion segment level, to simple macro models2,5,24,33,34 for studies of the mechanical behavior of the entire spinal column. Characteristic of a micro model is that very detailed studies can be done, but an overview is not possible.…”

Section: Introductionmentioning

confidence: 99%

Numerical Simulation of Asymmetrically Altered Growth as Initiation Mechanism of Scoliosis

2007

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Abstract-The causes of idiopathic scoliosis are still uncertain; buckling is mentioned often, but never proven. The authors hypothesize another option: unilateral postponement of growth of MM Rotatores or of ligamentum flavum and intertransverse ligament. In this paper, both buckling and the two new theories of scoliotic initiation are studied using a new finite element model that simulates the mechanical behavior of the human spine. This model was validated by the stiffness data of Panjabi et al. (J. Biomech. 9:185-192, 1976). After a small correction of the prestrain of some ligaments and the MM Rotatores the model appeared to be valid. The postponement in growth was translated in the numerical model in an asymmetrical stiffness. The spine was loaded axially and the resulting deformation was analyzed for the presence of the coupling of lateral deviation and axial rotation that is characteristic for scoliosis. Only unilateral postponement of growth of ligamentum flavum and intertransverse ligament appeared to initiate scoliosis. Buckling did not initiate scoliosis.

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“…One important potential of computational models is that they enable the hypotheses about complex biological systems to be corroborated or ruled out and hence constantly add to our knowledge about them (Nigg and Herzog 2001;Viceconti 2010). Computational models of the biomechanics of the skeletal system and cardiovascular system have significantly advanced in recent years and have added to our knowledge of the role of biomechanics in the progression of pathological conditions such as skeletal deformities (Subbaraj et al 1989), the development of aneurysms (Watton et al 2010), fracture and wound healing (Geris et al 2010a,b), and medical device implantations and their prognosis (Zahedmanesh and Lally 2009;Zahedmanesh et al 2010;Caiazzo et al 2009;Boyle et al 2010). One important complexity that is specific to biomechanical systems is their regenerative ability where their structure can adapt in order to maintain homeostasis following any mechanical or biological perturbations.…”

Section: Introductionmentioning

confidence: 99%

A multiscale mechanobiological modelling framework using agent-based models and finite element analysis: application to vascular tissue engineering

Zahedmanesh

Lally

2011

Biomech Model Mechanobiol

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Computational models of mechanobiological systems have been widely used to provide insight into these systems and also to predict their behaviour. In this context, vascular tissue engineering benefits from further attention given the challenges involved in developing functional low calibre vascular grafts with long-term patency. In this study, a novel multiscale mechanobiological modelling framework is presented, which takes advantage of lattice-free agent-based models coupled with the finite element method to investigate the dynamics of VSMC growth in vascular tissue engineering scaffolds. The results illustrate the ability of the mechanobiological modelling approach to capture complex multiscale mechanobiological phenomena. Specifically, the framework enabled the study of the influence of scaffold compliance and loading regime in regulating the growth of VSMCs in vascular scaffolds and their role in development of intimal hyperplasia (IH). The model demonstrates that low scaffold compliance compared to host arteries leads to increased luminal ingrowth and IH development. In addition, culture of a tissue-engineered blood vessel under a pulsatile luminal pressure reduced luminal ingrowth and enhanced collagen synthesis within the scaffold compared to non-pulsatile culture. The mechanobiological framework presented provides a robust platform for testing hypotheses in vascular tissue engineering and lends itself to use as an optimisation design tool.

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Presurgical finite element simulation of scoliosis correction

Cited by 13 publications

References 6 publications

Finite element simulation of a scoliotic spine with periodic adjustments of an attached growing rod

Finite element simulation of a scoliotic spine with periodic adjustments of an attached growing rod

Numerical Simulation of Asymmetrically Altered Growth as Initiation Mechanism of Scoliosis

A multiscale mechanobiological modelling framework using agent-based models and finite element analysis: application to vascular tissue engineering

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