Pressure–volume Index‐based Volume Calculation of Contrast Medium for Atlanto‐occipital Myelography in Dogs

Abstract

Subarachnoid pressure recordings were made during atlanto-occipital myelography in 45 dogs with clinical signs of spinal disease. Iohexol was injected at a dosage of 0.3 ml/kg body weight and simultaneous pressure values were recorded in the cerebellomedullary cistern. The mean subarachnoid pressure was 9 ± 3 mmHg before and 70 ± 32 mmHg at the end of administration. From the pressure change induced by the volume load, the pressure-volume index (PVI) of the subarachnoid space was calculated and found to be in close correlation with body weight and the crown-rump length (r = 0.94 and 0.87). Using the estimated PVI values, the appropriate volume of contrast medium can be calculated for an animal according to body weight. Dogs of a large body size require relatively less contrast medium than small-sized dogs (range 0.17-0.35 ml/kg). This calculated volume is unlikely to increase the subarachnoid pressure above 40 mmHg as a specific pressure limit. Using these data, simplified recommendations for the choice of contrast medium volumes have been generated.

Subarachnoid pressures and cardiorespiratory parameters during cisternal myelography in isoflurane anaesthetized dogs

“…Reconsideration of contrast medium dose was also a subject of this present study, the details of which are published elsewhere (Arany‐Toth et al. ).…”

“…The pressure‐volume index of the CSF space during myelography on these same dogs has been published elsewhere (Arany‐Toth et al. ).…”

Comparison Between Magnetic Resonance Imaging Estimates of Extracranial Cerebrospinal Fluid Volume and Physical Measurements in Healthy Dogs

“…To the best of our knowledge, no published information exists on the overall volume of the extracranial canine cerebrospinal fluid (CSF). One study applied iohexol into the subarachnoid (SA) space of dogs using a constant dosage system (0.3 ml/kg) and recorded the pressure of the SA space . As the pressure increased in larger dogs significantly more than in smaller dogs, findings from this previous study suggested that larger dogs could have smaller proportional CSF volumes.…”

Effects of lumbar myelography on subarachnoid pressure and cardiorespiratory parameters in healthy sheep

“…Despite of modern modalities of diagnostic imaging, such as computed tomography and magnetic resonance imaging, myelography remains important, especially due to its specificity and sensitivity for identifying spinal cord compressions (Arany-Tóth et al 2012).…”

“…Epileptic crisis is considered the most prevalent and important one (Barone et al 2002). Among other causes, the increase of subarachnoid pressure deserves to be highlighted once it can contribute, potentially, to adverse effects (Arany-Tóth et al 2012).…”