Inspite of improvements in medical industry and healthcare, pressure ulcers prevention remains high in hospitalized patients. These pressure ulcers prevails mostly in the patients who stays in hospital for long-term, assisted living at home, paralysed patients and with other physical disorders excluding of their diagnosis and health care needs. Pressure ulcers are known as a kind of skin lesion which influences the patient’s integrity of life and their caregiver become an significant reason of morbidity and in some aspects increase in the mortality. Managing and treating pressure ulcers are too costly. Though many devices have been designed with the aim of pressure ulcer prevention and cure but most of the existing technically complex devices have been exposed to be no more efficient and cost effective. Prevalence of these ulcers can be achieved by reducing pressures at bony prominences since pressure ulcers are high-cost and high adverse event. The objective of this manuscript is to review recent articles, with particular emphasis on prevention of bedsore in physically disabled patients.