Behaviour of bulk phonons propagating in clathrate compounds based on thiourea has been studied by Brillouin spectroscopy for different polarizations of incident and scattered beams. Elasto-optical coefficients p12, p13, p44 and p31 have been determined for host–guest type crystals. Pressure dependence of the intensity of excitations propagating in a structure of the host–guest type has been studied by the non-invasive method of Brillouin spectroscopy.