1974
DOI: 10.1017/s0022172400023706
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Preservation of corynebacteriophages by freeze-drying

Abstract: SUMMARYA method of freeze-drying is described by which the activity of a series of corynebacteriophages was maintained over a test period of 30 months, whereas some of these strains became inactive if stored as liquid filtered lysates at 4° C, or frozen and held at − 25° C.

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Cited by 9 publications
(8 citation statements)
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“…The level of stabilization afforded by sugars generally depends on their concentration [21]. The results of a number of studies [7], [10], [11], [12] show that various concentrations are optimal for different phages. Therefore, four different concentrations of each of these stabilizers, i.e.…”
Section: Resultsmentioning
confidence: 99%
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“…The level of stabilization afforded by sugars generally depends on their concentration [21]. The results of a number of studies [7], [10], [11], [12] show that various concentrations are optimal for different phages. Therefore, four different concentrations of each of these stabilizers, i.e.…”
Section: Resultsmentioning
confidence: 99%
“…Thus far, phages have been lyophilized most frequently in normal culture media with addition of gelatin, peptone and some sugars at different concentrations [10], [11], [12], [13]. It is also important to notice that most of the stabilizers used in the studies at the end of the last century with the aim to optimize phage storage conditions, nowadays are not pharmaceutically acceptable any more.…”
Section: Resultsmentioning
confidence: 99%
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