Préservation de la fertilité masculine

Saïas-Magnan, J.; Perrin, Jeanne; Metzler‐Guillemain, Catherine; Delotte, J.; Courbière, Blandine; Fatfouta, I.; Lattes, Sergio; Grillo, Jean-Marie; Thibault, Emmanuel

doi:10.1007/s10269-013-2286-6

Cited by 4 publications

(2 citation statements)

References 27 publications

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“…The rate of TQE in the cohort was similar in couples who achieved live births after AID cycles and in unsuccessful couples (Leguy et al, 2011). By contrast, another study showed that when couples had morphologically good embryos, the pregnancy rate was above 19% per cycle, whereas it was under 6% per cycle when couples had only morphologically poor embryos after ICSI cycles (Saias-Magnan & Mandelbaum, 2000). Overall, in our series, the LBR after six AID cycles was 68% and 54.5% for couples with and without TQE in previous ICSI cycles, respectively.…”

Section: Discussioncontrasting

confidence: 73%

“…Other studies analysing ICSI cycles have reported that certain parameters might act as prognostic factors for future ART with donor semen. It has been shown that a poor ovarian response to stimulation and poor morphological embryo quality in ICSI could have a negative impact on the pregnancy rate (Saias-Magnan & Mandelbaum, 2000). Moreover, male indications for ICSI (azoospermia, cryptozoospermia or oligoasthenozoospermia) may also negatively influence AID issues (Benchaib, 2010;Leguy et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

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Clinical outcome after insemination with donor sperm in patients with poor results in ICSI cycles

et al. 2012

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The introduction of intracytoplasmic sperm injection (ICSI) provided an effective treatment for infertile couples whose infertility was attributed to male factors. However, some of them face poor results after ICSI and subsequently use artificial insemination with donor sperm (AID). Only a few studies have reported on the clinical outcome of AID cycles after previous failed ICSI cycles, with contrasting results. The results reported here involve a cohort of 47 couples undertaking 175 AID cycles after 120 failed ICSI cycles for various reasons. Couples were allocated to two groups according to the availability of top quality embryos (TQE) in ICSI cycles. In our series, AID was successful for couples with and without TQE previously transferred in ICSI cycles, the live birth rate (LBR) per cycle being 20.0% and 13.3%, respectively. However, couples with TQE tended to succeed more rapidly than couples with poor quality embryos, with a higher cumulative LBR (68.0% versus 54.5%, respectively). These findings demonstrate that even couples with a history of unsuccessful ICSI cycles because of poor embryo quality are able to achieve high LBR after AID cycles. However, such couples have a lower cumulative LBR and are required to be more patient to achieve parenthood.

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Section: Discussioncontrasting

confidence: 73%

Section: Introductionmentioning

confidence: 99%