Present-Day Concepts of Shock

The Influence of Stress upon Liver Function in Obstructive Jaundice

“…They also noted an increase in the prothrombin time but little change in the sulfobromophthalein excretion and the level of serum phosphatase. A more recent study of the effect of hemorrhagic shock in dogs by Frank,6 in 1953, reports an increase in blood sugar concentration, a decrease in liver glycogen, a delay in regeneration of plasma albumin, prothrombin, and fibrinogen, an impairment in the galactose toler¬ ance test, and little change in the excretion of sulfobromophthalein.…”

The Role of Halothane in the Prevention of Surgical Shock

“…The study of shock has occupied the minds of medical men for over two centuries and the documentation has reached relatively enormous proportions. Several excellent reviews of the literature have been published (Nelson, 1957;Millican and Rosenthal, 1954;Frank, 1953;Drew, 1942). These reviews indicate that most of the work to date has been done by surgeons, physicians, and physiologists who have proved conclusively that the maintenance of the blood volume is the most important single factor in the prevention and treatment of shock.…”