Presence and impact of allelic variations of two alternative s‐kdr mutations, M918T and M918L, in the voltage‐gated sodium channel of the green peach aphid Myzus persicae

Abstract

This work provides more information about the new s-kdr M918L mutation in M. persicae, describing a more complicated situation arising from the possible combination with the classic L1014F and M918T. Our data open new questions concerning the origin of these new genotypes with different combinations of target-site mutations, and also their possible influence on control strategies.

Unintentional exposure to terrestrial pesticides drives widespread and predictable evolution of resistance in freshwater crustaceans

“…The M918L mutation frequencies in the Chualar Ceek H. azteca population were much higher (L TTG = 0.70 and L CTG = 0.15) than the same mutation frequencies (less than 0.5) found in populations of the green peach aphid, Myzus persicae documented by Panini et al. (). It is possible that the Chualar Creek H. azteca in our study had higher frequencies of M918L because it is functionally more favored in H. azteca than in M. persicae .…”

“…In addition to identifying the same L925I and M918L resistance mutations we previously identified in H. azteca (Weston et al., ), we also found two novel resistance alleles in H. azteca : the M918L conferred by a TTG codon rather than CTG and the L925V amino acid substitution. The M918L TTG and the M918L CTG were both identified in the Chualar Creek (HighPU) population, and have also been identified in populations of the green peach aphid, M. persicae (Panini et al., ). The leucine‐to‐valine (L925V) amino acid substitution was identified in some H. azteca from Mosher Slough (HighPU).…”

Discovery of metabolic resistance to neonicotinoids in green peach aphids (Myzus persicae) in Australia

“…Mutation S431F of the acetylcholinesterase enzyme results in resistance to dimethyl carbamates. Several mutations (L1014F, M918T, M918L) in the voltage‐gated sodium channel individually and/or in combination confer resistance to pyrethroids …”

“…Several mutations (L1014F, M918T, M918L) in the voltage-gated sodium channel individually and/or in combination confer resistance to pyrethroids. 7,8 Although several other chemical groups are registered for M. persicae control in some crops (e.g. tetramic acids, sulfoximines), neonicotinoids are often considered to be the 'final frontier' of insecticide control for M. persicae within Australia.…”

Special Issue to mark the career and retirement of Professor Gerry Brooks as the Editor‐in‐Chief of Pest Management Science

“…Most of the collection of articles in this special issue have been written by former or current colleagues of Gerry, from throughout his long and illustrious career. Gerry was born in 1930 and attended school in Nottingham, England, before studying chemistry at London University.…”