Perceiving one's romantic relationship as socially marginalized (i.e., as lacking social approval and acceptance) has been linked to an array of worse relational outcomes, including a greater likelihood of breakup. The present research extended this line of work by examining whether individuals who perceive disapproval specifically because of their current romantic relationship tend to experience worse personal health as well. Using an internet-based sample of romantically involved individuals, this study revealed that perceived marginalization of one's relationship was associated with reporting more symptoms of poor physical health, as well as lower self-esteem. Each of these associations was mediated by negative affect. Moreover, perceived marginalization was directly associated with engagement in riskier health behaviors, including more cigarette smoking and less frequent condom use. These associations remained, even when controlling for important personal and relationship characteristics. Thus, perceiving that one's relationship is socially marginalized is associated with worse health outcomes for the partners involved.Keywords discrimination, health, marginalized relationships, negative affect, self-esteem, social disapproval Individuals who perceive their romantic relationships as socially marginalized (i.e., as the targets of disapproval by their social networks and/or society at large) tend to