Prescribing pattern of gastroprotective agents with non-steroidal anti-inflammatory drugs

Drug utilization 90%: an innovative method in assessing quality of drug prescription with specific reference to non-steroidal anti-inflammatory drugs prescription

“…Overall diclofenac was the commonest NSAID prescribed in this study, same trend was observed in Dhaka prescription study. 8 Similarly diclofenac was also the commonest NSAID prescribed in a study conducted by VS Manohar et al 9 In this present study none of the selective cyclooxygenase-2 (COX-2) inhibitors were prescribed, instead preferential COX-2 inhibitors (diclofenac, etodolac and aceclofenac) and traditional NSAIDs (like piroxicam) were more preferred.…”

“…11 This changing trend might be due to increased awareness and recent reports of cardiovascular (CVS) complications associated with various selective COX-2 inhibitors. 9 Similarly a study conducted in New York, shows that COX-2 inhibitors constituted 37% of NSAID prescription before the withdrawal of rofecoxib. After withdrawal, their frequency decreased to 16% within one year and progressively decreased further in follow up studies.…”

“…16 In our study ranitidine was the commonest GPA prescribed and was more preferred than pantoprazole, unlike the study done by VS Manohar et al where proton pump inhibitors were more preferred. 9 In this study NSAID containing FDCs are prescribed in large numbers (n=160). Diclofenac+Chymotrypsin combination is the commonest FDC prescribed followed by Etodolac+Paracetamol, aceclofenac+paracetamol, tramadol + paracetamol and others.…”

An Exploratory Study on the Consumers Use of Medicine in the State of Sarawak, Malaysia

“…5 For example, consumers in different geographical settings use medicines differently due to the variation in the demographic and social economic status, differences in the resources allocation and the disparities in healthcare workforce supply. 6,7 Keyes et al study observed significant differences in the use of nonmedical prescription opioid between the urban and rural population. 8 In addition, Zhang et al found differences in healthcare service utilization between rural and urban women.…”

Evaluation of analgesics use in orthopedic department at tertiary care hospital in Bareilly, Uttar Pradesh, India

“…Gastrointestinal toxicity is a major clinical limitation. 5,6 Therefore, periodic evaluation of drug utilization patterns needs to be done to enable suitable modifications in the prescription of drugs to increase the therapeutic benefit and decrease the adverse effects. Prescribing pattern studies are conducted to monitor, evaluate and if necessary, suggest modifications in the prescribing behavior of medical practitioners to make medical care rational and cost effective.…”