Prescribing pattern of antidepressants in psychiatric unit of a tertiary care hospital

Avanthi, E.; Somashekar, H. S.; Kumar, L Pradeep; Sushma, H. K.; Sudarshan, C Y; Raja, Babbol

doi:10.5455/2319-2003.ijbcp20140820

Cited by 7 publications

(12 citation statements)

References 3 publications

(3 reference statements)

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“…Out of 196 prescriptions analyzed, male-to-female ratio was 1:1.17, correlating with the fact that depression is higher in females, which is consistent with studies by Grover et al, [11] Memon and Patel [12] , and Avanthi et al [13] Majority of patients were in the age group of 30-51 years in both sexes, which is similar to those reported in studies by Dutta et al, [14] Trivedi et al [15] , and Grover et al [11] Pediatric and geriatric groups together constituted less than 10% of our patient population, which is comparable to a previous study. [12] Depression was more common among housewives, which is comparable to a previous study.…”

Section: Discussionsupporting

confidence: 88%

“…[12] Depression was more common among housewives, which is comparable to a previous study. [13] It was found that 20.20% antidepressants were prescribed in our study. SSRIs were the most commonly prescribed class of antidepressants followed by SNRIs, which is consistent with that reported in a study by Dutta et al and other previous studies .…”

Section: Discussionmentioning

confidence: 54%

“…Better tolerability, combined with their mild adverse effects, accounts for their popularity as the most widely prescribed antidepressants. [13,18] Current treatment guidelines mostly recommend use of SSRIs as the first-line agents in patients of depression. [19] Out of total antianxiety drugs prescribed, majority were benzodiazepines, which is consistent with that reported in previous studies.…”

Section: Discussionmentioning

confidence: 99%

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A psychotropic drug use study among depression patients attending private psychiatric practitioners of Dehradun, Uttarakhand

Dutta¹,

Kaul²,

Beg³

et al. 2015

Int J Med Sci Public Health

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Background: Drug use studies are beneficial in clinical practice for rational prescribing of drugs and helpful for minimizing the medication errors. Aims and Objectives:The present study investigates the prescribing pattern of various antidepressants among private practitioners of Dehradun, Uttarakhand. Materials and Methods:A retrospective observational study was carried out in a private psychiatric unit at Dehradun. A total of 196 prescriptions were analyzed using World Health Organization drug use indicators and National Essential Medicine List (NEML) 2013.Results: Among 196 prescriptions, 54.08% were for females and 45.92% were for males. Depression was more commonly seen in patients in aged 31-50 years. Depression was more common among housewives (28.06%) and in married (52.04%) people. Selective serotonin reuptake inhibitors (SSRIs) (39.17%) were the most commonly prescribed class of antidepressants followed by serotonin norepinephrine reuptake inhibitors (33.33%). Fluoxetine and escitalopram were the most commonly prescribed SSRIs. Alprazolam (59.33%) was most commonly prescribed benzodiazepine class followed by lorazepam (16.0%) for comorbid anxiety symptoms. Among patients, 18.48% antipsychotics were prescribed to patients; olanzapine and risperidone (atypical antipsychotics) were the most commonly prescribed. Trihexyphenidyl was the most common anticholinergic prescribed. The average number of drugs per prescription in our study was 3.03 with 55.39% drugs prescribed from the NEML 2013.Conclusion: Fluoxetine and escitalopram were the most commonly used SSRIs. SSRIs are preferred over other antidepressants because of their relative lesser side effects. Polypharmacy was observed with benzodiazepines as frequent coprescription.Abstract Dutta et al.: A psychotropic drug utilization study

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 54%

Section: Discussionmentioning

confidence: 99%

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A psychotropic drug use study among depression patients attending private psychiatric practitioners of Dehradun, Uttarakhand

Dutta¹,

Kaul²,

Beg³

et al. 2015

Int J Med Sci Public Health

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“…This would enhance rational prescribing and affordability. In contrast to the findings of this study, SSRIs were the most frequently prescribed drugs in studies carried out in Asia, Europe, North America and India [3,14,15,21,[31][32][33][34] with decreased use of TCAs. Factors such as differences in culture, practice, promotional activity [32,35,36] and national income [37] contribute to these regional differences.…”

Section: Discussioncontrasting

confidence: 52%

Drug utilization patterns of antidepressants in Federal Neuro-Psychiatric Hospital Lagos, Nigeria

Kehinde

Anyika

Abah

2017

JHA

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Backgroud: The paucity of information on prescribing patterns and use of antidepressants in accordance with practice guidelines necessitated this study in Nigeria. Objective: To assess the prescribing patterns of antidepressants, average cost of prescriptions and the index of rational drug prescribing (IRDP) in a Nigerian tertiary care hospital. Methods: A retrospective study which involved the assessment of 683 prescriptions and case records of patients who received antidepressants from 1 st January 2013 to 31 st December 2014 was conducted. Information on diagnosis, patients' demographics, prescribing patterns and cost of medications was obtained therefrom. Compliance to the World Health Organization (WHO) prescribing indicators and Nigerian Standard Treatment Guidelines (STG) was assessed. The IRDP for antdepressants was determined using a validated mathematical model. The statistical analysis was performed using SPSS version 20. Results: Tricyclic antidepressants (TCAs) were the most commonly prescribed drug group (61.3%), followed by selective serotonin re-uptake inhibitors (SSRIs) with a total of 38.7%. On the average, three drugs were prescribed per prescription, while 60.3% and 38.3% of the drugs were prescribed from National Essential Medicine List (NEML) and STG respectively. The IRDP was 3.96 over 5 points. The average cost of drugs per prescription was 4.2 USD. The cost of drugs in the prescriptions written according to STG was lower compared to that in prescriptions not compliant with the STG (p < .001).Conclusions: TCAs are the most commonly prescribed antidepressants due to their affordability. The generic prescribing, medicines prescribed from the NEML and in compliance with the STG were less than the WHO standard. The rational drug use is suboptimal. Better prescribing habits, affordability and use of newer antidepressants should be encouraged by the hospital management.

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“…14 The average number of drugs per prescription is important in psychiatry as polypharmacy and misuse of psychotherapeutic drugs is common. 19 In our study the average number of drugs prescribed per prescription was 8.73 which were very high indicating polypharmacy. It was higher than the previous studies.…”

Section: Discussionmentioning

confidence: 92%

Recent scenario on psychotropic drug usage pattern among patients attending psychiatric outpatient department of a tertiary care teaching hospital in Nepal

Kaul

Beg²,

Dutta³

et al. 2016

Int J Basic Clin Pharmacol

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Prescribing pattern of antidepressants in psychiatric unit of a tertiary care hospital

Cited by 7 publications

References 3 publications

A psychotropic drug use study among depression patients attending private psychiatric practitioners of Dehradun, Uttarakhand

A psychotropic drug use study among depression patients attending private psychiatric practitioners of Dehradun, Uttarakhand

Drug utilization patterns of antidepressants in Federal Neuro-Psychiatric Hospital Lagos, Nigeria

Recent scenario on psychotropic drug usage pattern among patients attending psychiatric outpatient department of a tertiary care teaching hospital in Nepal

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