“…For example, the current study established the presence of terpenoids in all extracts in varying concentrations and flavonoids in A. pluriseta and C. pareira. Other studies have shown that flavonoids have antituberculous activity and they function mechanistically by inhibiting de novo fatty acid biosynthesis in Mycobacteria, inhibiting mycolic acid biosynthesis, proteasome inhibition, topoisomerase inhibition, inhibition of phosphatidyl-inositol 3-kinase, induction of cell cycle arrests, accumulation of p53 or enhanced expression of c-fos and c-myc genes (Yuan et al, 2009;Mariita et al, 2010b). Flavonoids have also been shown to have antimicrobial activity and to act by complexing microbial proteins and disrupting microbial membranes (Cowan, 1999;2003;Al-Bayati and Al-Mola, 2008;Samy and Gopalakrishnakone, 2008;Kaur and Arora, 2009;Ngoci et al, 2011Ngoci et al, , 2012.…”