Preparative separation of flavonoids in Adinandra nitida leaves by high-speed counter-current chromatography and their effects on human epidermal carcinoma cancer cells

Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of ethanol extract and pure flavonoids fromAdinandra nitidaleaves

“…It is reported to have many curative effects such as reducing blood pressure, as well as antibacterial, antioxidant, and analgesic properties (Wang et al, 2003). According to our previous studies Yuan et al, 2008Yuan et al, , 2009, the total flavonoid content in A. nitida leaves was more than 20% with camellianin A as the main flavonoid. Today, A. nitida has been cultivated in Guangxi province, China, so there is the possibility of large-scale application of flavonoids from A. nitida leaves in functional food and medicine.…”

“…In our previous study (Yuan et al, 2009), the method of preparing camellianin A and camellianin B by using high-speed counter-current chromatography (HSCCC) was established. But for the low content of camellianin B in A. nitida leaves, it was difficult to obtain enough camellianin B by HSCCC.…”

Potency of extracts of selected plant species from Mbeere, Embu County-Kenya against Mycobacterium tuberculosis

“…For example, the current study established the presence of terpenoids in all extracts in varying concentrations and flavonoids in A. pluriseta and C. pareira. Other studies have shown that flavonoids have antituberculous activity and they function mechanistically by inhibiting de novo fatty acid biosynthesis in Mycobacteria, inhibiting mycolic acid biosynthesis, proteasome inhibition, topoisomerase inhibition, inhibition of phosphatidyl-inositol 3-kinase, induction of cell cycle arrests, accumulation of p53 or enhanced expression of c-fos and c-myc genes (Yuan et al, 2009;Mariita et al, 2010b). Flavonoids have also been shown to have antimicrobial activity and to act by complexing microbial proteins and disrupting microbial membranes (Cowan, 1999;2003;Al-Bayati and Al-Mola, 2008;Samy and Gopalakrishnakone, 2008;Kaur and Arora, 2009;Ngoci et al, 2011Ngoci et al, , 2012.…”

Ultrasonic-Assisted Extraction and Antioxidant Activity of Flavonoids from <i>Adinandra nitida</i> Leaves

“…It is reported to have many curative effects, such as reduction of blood pressure, antibacterial, antitumor, anti-toxicity, and analgesic activities. It has been reported that the flavonoid content of its leaves could be > 20 % [1][2][3].…”