Preparative liquid chromatography

Hybrid method of solution applied to simulation of pulse chromatography

“…Simplified models, such as transport-dispersive or equilibrium-dispersive, can be adjusted to experimental data. It has been shown that a general rate model (GR) should be preferred for prediction, since their coefficients do not need to be adjusted with experimental results (Guiochon, 2002). In the present work, these coefficients were predicted by correlations from literature, as showed at Table 1.…”

Development and Validation of Analytical Methods for Pharmaceuticals

“…DAD detectors have been proposed for various applications, such as preliminary identification of a steroidal glycoside in seed [35], peptide mapping [36], assay of sulfamethazine in animal tissues [37], or identification of pesticides in human biological fluids [38].…”

Determination of Pesticides in Complex Samples by One Dimensional (1D-), Two-Dimensional (2D-) and Multidimensional Chromatography

“…Dzido et al (Dzido et al, 2002) also described the effect of temperature on the separation of test solutes in preparative TLC. Guiochon and colleagues (Guiochon, 2002;Felinger and Guiochon, 1998;Jandera et al, 1997;Gritti and Guiochon, 2003) described theory, instruments, and practical issues of preparative chromatography. The separation of a certain target component from a multicomponent mixture using isocratic preparative elution chromatography was also studied theoretically (Shan and SeidelMorgenstern, 2003 Also possible is the use of NP or RP systems with different retention mechanisms on hydrophilic modified stationary phases, e.g., cyanopropyl, aminopropyl, and diol.…”