Preparation of medical hydrophilic and antibacterial silicone rubber <i>via</i> surface modification

Ding, Xuejia; Wang, Yue; Liu, Shuaizhen; Wang, Sen; Mi, Jianguo

doi:10.1039/d1ra06260c

Cited by 11 publications

(6 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…30 Furthermore, studies have also shown that a hydrophilic surface or coating shows better antibacterial activity. 31 This is because a hydrophilic surface increases the contact area of the antibacterial material with the pathogens. 30 Bacteria coming in contact with a hydrophilic surface get adsorbed on the surface very easily through rapid spreading, thereby exposing it to a larger surface area of the antibacterial material.…”

Section: Fabrication and Characterization Of Mcp Glycosheet-coated Ss...mentioning

confidence: 99%

Biocompatible quaternary pullulan functionalized 2D MoS₂ glycosheet-based non-leaching and infection-resistant coatings for indwelling medical implants

Roy,

Haloi,

et al. 2023

J. Mater. Chem. B

View full text Add to dashboard Cite

show abstract

Section: Fabrication and Characterization Of Mcp Glycosheet-coated Ss...mentioning

confidence: 99%

Biocompatible quaternary pullulan functionalized 2D MoS₂ glycosheet-based non-leaching and infection-resistant coatings for indwelling medical implants

Roy,

Haloi,

et al. 2023

J. Mater. Chem. B

View full text Add to dashboard Cite

show abstract

“…[80] It is described that the in-crease of surfaces hydrophobicity can reduce the interaction between the bacteria and the surface by the formation of a hydration layer due the higher tension between hydrophilic surfaces with water. [81,82] Indeed, Yuan et al [83] showed that surfaces with CA of about 90°presented lower ABA of E. coli, decreasing the adhesion with a lower or higher wettability. Consequently, it is expected that surfaces with higher CA present lower bioaffinity.…”

Section: Assessment Of Antibacterial Adhesionmentioning

confidence: 99%

Green‐Based Modifications of Polyethylene Surfaces Enhancing Antifouling Properties in Water‐Related Systems

Vieira,

Rodríguez‐Lorenzo,

Garrido‐Maestu

et al. 2023

Adv Materials Technologies

View full text Add to dashboard Cite

The effects of fouling in plastics, such as polyethylene (PE), can have a major economic impact due to tube clogging and other issues. Surface properties, both chemical and physical, can substantially influence biofilm formation, so developing antifouling materials through engineering these properties is very promising. In this work, two main approaches are evaluated for reducing the fouling on PE surfaces: chemical modification with green coating (polyethylene glycol (PEG) and different chitosan nanoparticles (CS NPs)) and physical modification with distinct micro‐topographies. First, the antibacterial adhesion is tested with Escherichia coli. The results reveal that CS NPs result in a considerable decrease in adhesion depending on which source of chitosan is used. PEG coating only reduced adhesion by 26%, while CS NPs with a high molecular weight (CS3) decreased adhesion by 88% in relation to non‐modified surfaces. Moreover, lozenges topographic modification (T2) has the highest effect on the bacteria adhesion within the physically‐modified PE surfaces. Finally, CS3 and T2 surfaces are tested in water samples in dynamic conditions for 27 days and results showed lower bacterial adhesion than unmodified surfaces. Overall, both strategies offer eco‐friendly and cost‐effective solutions for preventing fouling and extending the lifetime of polymeric surfaces for environmental applications.

show abstract

“…Medical-grade silicone (MGS) is the primary material in endotracheal prostheses. MGS has attractive properties such as chemical inertness, water and temperature resistance, biocompatibility, and flexibility [ 11 ]. The constant contact between the inhaled air passing through the airway prosthesis and the tracheal underlying mucosa promotes the accumulation of biofilms composed of bacteria and fungi.…”

Section: Introductionmentioning

confidence: 99%

Cold Atmospheric Helium Plasma in the Post-COVID-19 Era: A Promising Tool for the Disinfection of Silicone Endotracheal Prostheses

Silva,

Do Nascimento,

Milhan

et al. 2024

Microorganisms

View full text Add to dashboard Cite

Despite the excellent properties of silicone endotracheal prostheses, their main limitation is the formation of a polymicrobial biofilm on their surfaces. It can cause local inflammation, interfering with the local healing process and leading to further complications in the clinical scenario. The present study evaluated the inhibitory effect of cold atmospheric plasma (CAP) on multispecies biofilms grown on the silicone protheses’ surfaces. In addition to silicone characterization before and after CAP exposure, CAP cytotoxicity on immortalized human bronchial epithelium cell line (BEAS-2B) was evaluated. The aging time test reported that CAP could temporarily change the silicone surface wetting characteristics from hydrophilic (80.5°) to highly hydrophilic (<5°). ATR-FTIR showed no significant alterations in the silicone surficial chemical composition after CAP exposure for 5 min. A significant log reduction in viable cells in monospecies biofilms (log CFU/mL) of C. albicans, S. aureus, and P. aeruginosa (0.636, 0.738, and 1.445, respectively) was detected after CAP exposure. Multispecies biofilms exposed to CAP showed significant viability reduction for C. albicans and S. aureus (1.385 and 0.831, respectively). The protocol was not cytotoxic to BEAS-2B. CAP can be a simple and effective method to delay multispecies biofilm formation inside the endotracheal prosthesis.

show abstract

Preparation of medical hydrophilic and antibacterial silicone rubber via surface modification

Abstract: Surface modification of silicone rubber to enhance hydrophilicity and antibacterial effect.

Cited by 11 publications

References 35 publications

Biocompatible quaternary pullulan functionalized 2D MoS₂ glycosheet-based non-leaching and infection-resistant coatings for indwelling medical implants

Biocompatible quaternary pullulan functionalized 2D MoS₂ glycosheet-based non-leaching and infection-resistant coatings for indwelling medical implants

Green‐Based Modifications of Polyethylene Surfaces Enhancing Antifouling Properties in Water‐Related Systems

Cold Atmospheric Helium Plasma in the Post-COVID-19 Era: A Promising Tool for the Disinfection of Silicone Endotracheal Prostheses

Contact Info

Product

Resources

About

Preparation of medical hydrophilic and antibacterial silicone rubber via surface modification

Abstract: Surface modification of silicone rubber to enhance hydrophilicity and antibacterial effect.

Cited by 11 publications

References 35 publications

Biocompatible quaternary pullulan functionalized 2D MoS2 glycosheet-based non-leaching and infection-resistant coatings for indwelling medical implants

Biocompatible quaternary pullulan functionalized 2D MoS2 glycosheet-based non-leaching and infection-resistant coatings for indwelling medical implants

Green‐Based Modifications of Polyethylene Surfaces Enhancing Antifouling Properties in Water‐Related Systems

Cold Atmospheric Helium Plasma in the Post-COVID-19 Era: A Promising Tool for the Disinfection of Silicone Endotracheal Prostheses

Contact Info

Product

Resources

About

Biocompatible quaternary pullulan functionalized 2D MoS₂ glycosheet-based non-leaching and infection-resistant coatings for indwelling medical implants

Biocompatible quaternary pullulan functionalized 2D MoS₂ glycosheet-based non-leaching and infection-resistant coatings for indwelling medical implants