Preparation of magnetic molecularly imprinted polymer for dispersive solid‐phase extraction of valsartan and its determination by high‐performance liquid chromatography: Box‐Behnken design

Kaabipour, Maryam; Khodadoust, Saeid; Zeraatpisheh, Fatemeh

doi:10.1002/jssc.201901058

Cited by 20 publications

(11 citation statements)

References 21 publications

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“…Magnetic DSPE (MDSPE) is a form of DSPE in which a magnetic adsorbent is used to extract analytes. The ease of separation of the adsorbent by applying an external magnetic field from the non-magnetic matrix of the samples is the main reason behind its wide application [13,17].…”

Section: Introductionmentioning

confidence: 99%

Polycarbonate‐coated magnetic nanoparticles for the extraction of imipramine and its primary metabolite from urine

Sattari Dabbagh,

Farajzadeh,

Pirmohamadlou

et al. 2023

J of Separation Science

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This study introduces a reliable and inexpensive magnetic dispersive solid phase extraction to extract imipramine and its primary metabolite (desipramine) from urine samples. To accomplish this aim, Fe3O4 magnetic nanoparticles were synthesized by sonication, subsequently, polycarbonate was precipitated gradually onto the surface of them to form the adsorbent. Extraction recoveries of 85% and 76%, enrichment factors of 57 and 51, limits of detection of 2.5 and 2.8 μg/L, and limits of quantification of 8.3 and 9.3 μg/L were obtained for imipramine and desipramine under the optimal conditions, respectively. In addition, relative standard deviations for intra‐ (n = 6) and inter‐day (n = 5) precisions at two concentrations (50 and 100 μg/L of each analyte) were less than or equal to 4%. Short extraction time, good repeatability, high enrichment factors, and simplicity are the main advantages of the proposed method.

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Section: Introductionmentioning

confidence: 99%

Polycarbonate‐coated magnetic nanoparticles for the extraction of imipramine and its primary metabolite from urine

Sattari Dabbagh,

Farajzadeh,

Pirmohamadlou

et al. 2023

J of Separation Science

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“…Using the magnetic nanoparticles as the adsorbent, magnetic dispersive SPE (d-SPE) technology was developed to further simplify the sample preparation step [13][14][15]. Compared with the traditional SPE column, magnetic MIPs (MMIPs) could be directly dispersed into the extraction solvent to allow full contact with the target.…”

Section: Introductionmentioning

confidence: 99%

Development of hydrophilic magnetic molecularly imprinted polymers for the dispersive solid‐phase extraction of sulfonamides from animal‐derived samples before HPLC detection

Zhao

Lü

Zhu

et al. 2021

J of Separation Science

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Highly hydrophilic magnetic molecularly imprinted polymers were prepared through a surface imprinting technique for dispersive solid-phase extraction coupled with high-performance liquid chromatography to detect trace levels of ten sulfonamides in animal-derived samples. The obtained imprinted polymers were characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, thermogravimetric analysis, and adsorption experiments, which exhibited excellent specific adsorption for template sulfamethazine in aqueous solution. Moreover, the adsorption process could be completed within 25 min. Under the optimum conditions, the method exhibits good linear performance in the range of 5-to 10 mg/L, limits of detection ranging from 0.57 to 1.50 μg/L, and good recoveries of 85.09-110.93% in the spiked samples (chicken, cow milk, and goat milk). The proposed detection method not only avoids the use of organic solvents but also simplifies the pretreatment procedure via excellent magnetic properties. Furthermore, the method shows great potential for the rapid detection of drug residues.

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“…35 Dinali et al 36 developed a molecularly imprinted polymer for subsequent application in the extraction of trimethoprim and sulfamethoxazole residues in bovine milk. Kaabipour et al 37 synthesized core/shell MMIPs-NPs for extraction and pre-concentration of valsartan from water and urine samples followed by HPLC-UV.…”

Section: Introductionmentioning

confidence: 99%

Magnetic molecularly imprinted polymers for extraction of S‐phenylmercapturic acid from urine samples followed by high‐performance liquid chromatography

Shao

Shi

et al. 2021

J of Molecular Recognition

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In this study, magnetic molecularly imprinted polymers (MMIPs) were prepared and used as sorbents for extraction of S-phenylmercapturic acid (S-PMA) from urine samples, followed by high-performance liquid chromatography ultraviolet-visible (HPLC-UV/Vis) analysis. The MMIPs were synthesized by the copolymerization reaction of (phenylthio) acetic acid (template molecule), methacrylic acid (functional monomers) and ethylene glycol dimethacrylate (cross-linkers). The morphology, structure property and surface groups of the prepared MMIPs were characterized by scan electron microscopy, transmission electron microscopy, infrared spectroscopy, X-ray diffraction pattern, thermogravimetric analyses, Brunauer-Emmett-Teller and vibrating sample magnetometer. The selectivity of the MMIPs was investigated in the presence of interferents. Various parameters affecting the S-PMA extraction efficiency were investigated, including MMIPs amount, pH, sample volume, desorption solvent, as well as extraction and desorption time. The obtained optimal parameters were as follows: MMIPs amount (20 mg), pH (3.0), sample volume (5 mL), desorption solvent (methanol/acetic acid [9/1, v/v]), extraction time (30 minutes) and desorption time (2 minutes). The method was validated according to the Food and Drug Administration Guidance for Industry on Bioanalytical Method Validation. The calibration curve for the analyte was linear in the concentration range of 0.030-1.0 mg/L (r = 0.9995).The LOD and LOQ of the method were 0.0080 and 0.0267 mg/L, respectively. The enrichment factor of the MMIPs was 5. The relative standard deviations of intra-and inter-day tests were in the range of 3.8-5.1% and 3.9-6.3%, respectively. The recoveries at three different concentrations of 0.10, 0.50 and 0.80 mg/L ranged between 95.2% and 98.6%. In addition, the MMIPs could be reused for at least eight times.The proposed method was successfully applied to the determination of S-PMA in urine samples. In addition, this developed method could be used as a tool in the early screening and clinical diagnosis of benzene intoxication.

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Preparation of magnetic molecularly imprinted polymer for dispersive solid‐phase extraction of valsartan and its determination by high‐performance liquid chromatography: Box‐Behnken design

Cited by 20 publications

References 21 publications

Polycarbonate‐coated magnetic nanoparticles for the extraction of imipramine and its primary metabolite from urine

Polycarbonate‐coated magnetic nanoparticles for the extraction of imipramine and its primary metabolite from urine

Development of hydrophilic magnetic molecularly imprinted polymers for the dispersive solid‐phase extraction of sulfonamides from animal‐derived samples before HPLC detection

Magnetic molecularly imprinted polymers for extraction of S‐phenylmercapturic acid from urine samples followed by high‐performance liquid chromatography

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