Preparation of magnetic molecularly imprinted polymers by atom transfer radical polymerization for the rapid extraction of avermectin from fish samples

Abstract

A novel and highly efficient approach to obtain magnetic molecularly imprinted polymers is described to detect avermectin in fish samples. The magnetic molecularly imprinted polymers were synthesized by surface imprinting polymerization using magnetic multiwalled carbon nanotubes as the support materials, atom transfer radical polymerization as the polymerization method, avermectin as template, acrylamide as functional monomer, and ethylene glycol dimethacrylate as crosslinker. The characteristics of the magnetic molecularly imprinted polymers were assessed by using transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, vibrating sample magnetometry, X-ray diffraction, and thermogravimetric analysis. The binding characteristics of magnetic molecularly imprinted polymers were researched through isothermal adsorption experiment, kinetics adsorption experiment, and the selectivity experiment. Coupled with ultra high performance liquid chromatography and tandem mass spectrometry, the extraction conditions of the magnetic molecularly imprinted polymers as adsorbents for avermectin were investigated in detail. The recovery of avermectin was 84.2-97.0%, and the limit of detection was 0.075 μg/kg. Relative standard deviations of intra- and inter-day precisions were in the range of 1.7-2.9% and 3.4-5.6%, respectively. The results demonstrated that the extraction method not only has high selectivity and accuracy, but also is convenient for the determination of avermectin in fish samples.

Preparation and application of magnetic molecularly imprinted polymers for the isolation of chelerythrine from Macleaya cordata

“…Until now, magnetic nanoparticles, carbon nanotubes, graphene oxide, and silica particles have been used as sorbents and a support substrate for surface molecular imprinted polymers . Among these materials, magnetic separation technology combined with molecularly imprinted polymers has attracted remarkable attention in recent years for the fact that they not only exhibit specific selective binding for the template but also have high superparamagnetism for easy separation with an external magnet . Therefore, novel magnetic molecularly imprinted polymers (MMIPs) have been utilized in SPE for sample pretreatment .…”

Advanced materials on sample preparation for safety analysis of aquatic products

“…[30] Copyright 2020, American Chemical Society improve the extraction efficiency, avoid tedious operation, and realize recycle use [13,33]. Thus, magnetic materials are normally combined with other advanced functional materials to prepare magnetic adsorbent materials for the safety analysis of aquatic products samples [21,[34][35][36]. For example, Li et al [30] embedded CoFe 2 O 4 nanobeads into halloysite nanotubes (HNTs) with AuNPs modification as multifunctional CoFe 2 O 4 @HNTs/AuNPs substrate for rapid and efficient MSPE surface-enhanced Raman scattering (SERS) detection of nitrofuran in fish, shrimp, and fish feed all-in-one ( Figure 1).…”