Preparation of Hydrogel Nanocomposite Containing Gold Nanoparticles With Unique Swelling/Deswelling Properties

Wikantyasning, Erindyah Retno; Mutmainnah, M.; Cholisoh, Zakky; Hairunisa, I.; Bakar, M.F.A.; Dai, Ming

doi:10.31788/rjc.2019.1245209

Cited by 4 publications

(3 citation statements)

References 19 publications

(24 reference statements)

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“…The polymer (PAA) was synthesized using the previously synthesized the reversible addition-fragmentation chain (RAFT) agents[ 7 ] via the RAFT polymerization method. The polymer was then dialyzed against water for 2 days and lyophilized for 24 hours.…”

Section: Aterials and M Ethodsmentioning

confidence: 99%

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3-Aminophenylboronic Acid Conjugation on Responsive Polymer and Gold Nanoparticles for Qualitative Bacterial Detection

Wikantyasning

Da'i

Cholisoh

et al. 2023

Journal of Pharmacy and Bioallied Sciences

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Background: Because of their sensitive and selective responses to a wide variety of analytes, colorimetric sensors have gained widespread acceptance in recent years. Gold nanoparticles (AuNPs) are widely employed in visual sensor strategies due to their high stability and ease of use. Combining AuNPs with a responsive polymer can result in distinct surface plasmon resonance (SPR) changes that can be utilized as colorimetric biosensors. Objectives: The purpose of this research is to develop a colorimetric-based sensor through the utilization of the optical properties of gold nanoparticles (AuNPs) crosslinked with pH-responsive polymers poly (acrylic acid) (PAA) conjugated to 3-aminophenyl boronic acid (APBA). Methods: The polymer (PAA) was synthesized via RAFT polymerization. The inversed Turkevic method was used to produce AuNPs, which were subsequently used in a self-assembly process using poly (acrylic acid)-aminophenyl boronic acid (PAA-APBA) to create the self-assembled AuNPs-APBA-PAA. The particle size, zeta potential, and reversibility of the polymer-modified gold nanoparticles were determined using a transmission electron microscope (TEM), a particle size analyzer (PSA), and an Ultraviolet-Visible spectrophotometer (UV-Vis spectrophotometer). Visual, UV-Vis spectrophotometer and TEM observations confirmed the system’s ability to identify bacteria. Statistical analysis was performed using a one-way analysis of variance using Excel software. Results: Using UV-Vis spectrophotometry, the particle size of AuNPs was determined to be 25.7 nm, and the maximum absorbance occurred at 530 nm. AuNPs PAA APBA colloid exhibited an absorbance maximum of 532 nm, a zeta potential of -41.53, and a pH transition point between 4 and 5. At E. coli concentrations of 4.5 x 107 CFU/mL, the color of the system sensors changed from red to blue after 15 hours of incubation, whereas at S. aureus concentrations of 1.2 x 109 CFU/mL, the color changed to purple immediately after mixing. The TEM confirmed that the detection mechanism is based on the boronate-polyol bonding of saccharides on the outer membranes of Escherichia coli and Staphylococcus aureus. Conclusions: The use of APBA in conjunction with pH-responsive PAA polymers containing AuNPs to detect E. coli and S. aureus bacteria induces a maximum wavelength transition, followed by a color change from red to blue. By the process of de-swelling of the responsive polymer, which induces the aggregation of the AuNPs, the established sensor system is able to alter the color. The conjugated polymer and gold nanoparticle-based sensor system demonstrated a promising method for bacterial detection.

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Section: Aterials and M Ethodsmentioning

confidence: 99%

“…[ 6 ] In addition, AuNPs can be used as sensors for the detection of Escherichia coli bacteria by conjugating cysteine with polymers that are pH-responsive poly (acrylic acid). [ 7 ]…”

Section: Introductionmentioning

confidence: 99%

3-Aminophenylboronic Acid Conjugation on Responsive Polymer and Gold Nanoparticles for Qualitative Bacterial Detection

Wikantyasning

Da'i

Cholisoh

et al. 2023

Journal of Pharmacy and Bioallied Sciences

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“…15 Gold nanoparticles are prepared with poly (acrylic acid) and cysteine, it is characterized by techniques. 16 The present research studies have employed a new synthetic method for the preparation of the tri polymers of AA.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Cross-Linked Tri-Polymers of Poly Acrylic Acid as Water Thickening Agents

Patel¹,

Patel²,

P.M.Chatrabhuji³

et al. 2020

RJC

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A cross-linked poly acrylic acid tri-polymer is successfully synthesized by batch charging polymerization of poly allyl tris buffer, di-vinyl benzene and acrylic acid and this new method is profitable in terms of reducing the toxicity, faster, purity and cheaper than available methods. The morphological structure of the synthesized polymer is studied by SEM and the characteristic functional groups of the synthesized polymers are identified using FTIR. TGA and DSC techniques were employed to study their thermal characterization.

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Adsorption of thiotepa anticancer by the assistance of aluminum nitride nanocage scaffolds: A computational perspective on drug delivery applications

Ortiz

Cespedes-Panduro

Saba

et al. 2023

Colloids and Surfaces A: Physicochemical and Engineering Aspect

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Preparation of Hydrogel Nanocomposite Containing Gold Nanoparticles With Unique Swelling/Deswelling Properties

Cited by 4 publications

References 19 publications

3-Aminophenylboronic Acid Conjugation on Responsive Polymer and Gold Nanoparticles for Qualitative Bacterial Detection

3-Aminophenylboronic Acid Conjugation on Responsive Polymer and Gold Nanoparticles for Qualitative Bacterial Detection

Synthesis and Characterization of Cross-Linked Tri-Polymers of Poly Acrylic Acid as Water Thickening Agents

Adsorption of thiotepa anticancer by the assistance of aluminum nitride nanocage scaffolds: A computational perspective on drug delivery applications

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