Preparation, Characterization, and Antibacterial Effects of Chitosan Nanoparticles Embedded with Essential Oils Synthesized in an Ionic Liquid Containing System

Wu, Jianan; Shu, Qin; Niu, Yongwu; Jiao, Yingchun; Chen, Qihe

doi:10.1021/acs.jafc.8b01428

Cited by 46 publications

(14 citation statements)

References 37 publications

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“…Additionally, it damages the protein and DNA by releasing reactive oxygen species and thereby leading to cell death (Lee et al 2003; Sondi and Salopek-Sondi 2004). Besides, nanoparticles with MEL (IL-CS-Nano-MEL) exhibited stronger antibacterial effects against S. aureus than IL-CS-Nano, suggesting the antibacterial effects of MEL (Wu et al 2018).…”

Section: Discussionmentioning

confidence: 99%

Synthesis of gold nanoparticles derived from mannosylerythritol lipid and evaluation of their bioactivities

et al. 2019

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In this study, we introduce a simple and green method for synthesis of gold nanoparticles (AuNPs) using microbial glycolipid mannosylerythritol lipid (MEL) produced from Ustilago maydis CGMCC 5.203 and to evaluate their biomedical activities. MEL was found 10.3 g/L using sunflower oil. The formation of MEL-AuNPs was verified using UV–visible spectrum, XRD, TEM, FTIR, SEM, and EDX. In the biomedical examinations, MEL-AuNPs demonstrated potential cytotoxicity against HepG2 cells, and IC 50 values were found to be 100 and 75 µg/mL for 24 h and 48 h of exposure, respectively, which indicates its good performance against cancer cells. The IC 50 value of MEL-AuNPs was found to be 115 and 124 µg/mL for DPPH and ABTS scavenging activities, respectively. The biosynthesized MEL-AuNPs significantly inhibited cell growth of pathogenic Gram-positive and Gram-negative bacteria. These findings indicated that MEL plays a crucial role in the rapid biofabrication method of metallic NPs possessed the potential of biomedical activities.

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Section: Discussionmentioning

confidence: 99%

Synthesis of gold nanoparticles derived from mannosylerythritol lipid and evaluation of their bioactivities

et al. 2019

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“…Although the researches of MELs involved in nanomaterial synthesis are not as many as others, their applications in nanotechnology are emerging and advancing latterly. Firstly, Wu et al embedded chitosan nanoparticles into essential oils using MEL-A as an emulsifier and observed an apparent inhibition zone against Staphylococcus aureus around the chitosan-based nanoparticles [103]. Subsequently, Bakur et al successfully fabricated metallic nanomaterials including silver, zinc oxide, and gold nanoparticles mediated by MEL-A, and all of them exert inhibitory efficacy against pathogenic gram-positive and gram-negative bacteria [104].…”

Section: Glycolipid-modified Materials 31 Nanocompositesmentioning

confidence: 99%

Contributions of Glycolipid Biosurfactants and Glycolipid-Modified Materials to Antimicrobial Strategy: A Review

et al. 2021

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Glycolipid biosurfactants are natural amphiphiles and have gained particular interest recently in their biodegradability, diversity, and bioactivity. Microbial infection has caused severe morbidity and mortality and threatened public health security worldwide. Glycolipids have played an important role in combating many diseases as therapeutic agents depending on the self-assembly property, the anticancer and anti-inflammatory properties, and the antimicrobial properties, including antibacterial, antifungal, and antiviral effects. Besides, their role has been highlighted as scavengers in impeding the biofilm formation and rupturing mature biofilm, indicating their utility as suitable anti-adhesive coating agents for medical insertional materials leading to a reduction in vast hospital infections. Notably, glycolipids have been widely applied to the synthesis of novel antimicrobial materials due to their excellent amphipathicity, such as nanoparticles and liposomes. Accordingly, this review will provide various antimicrobial applications of glycolipids as functional ingredients in medical therapy.

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“…There are two possible ways to combat multidrug resistant pathogens along with EOs either by nano-encapsulation method or combination with bi-and tri-metallic NPs with EOs. Recently, Wu et al, prepared chitosan NPs embedded with Torreya grandis aril EOs and studied their antibacterial properties against S. aureus found stronger antibacterial activities than chitosan NPs alone [191]. Synergistic antibacterial activity of silver NPs with EOs of Kelussia odoratissima and Teucrium polium investigated their enhanced effect against multidrug-resistant bacteria [192].…”

Section: Interaction Of Essential Oils and Metallic Nanoparticlesmentioning

confidence: 99%

Essential Oils and Mono/bi/tri-Metallic Nanocomposites as Alternative Sources of Antimicrobial Agents to Combat Multidrug-Resistant Pathogenic Microorganisms: An Overview

2020

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Over the past few decades, many pathogenic bacteria have become resistant to existing antibiotics, which has become a threat to infectious disease control worldwide. Hence, there has been an extensive search for new, efficient, and alternative sources of antimicrobial agents to combat multidrug-resistant pathogenic microorganisms. Numerous studies have reported the potential of both essential oils and metal/metal oxide nanocomposites with broad spectra of bioactivities including antioxidant, anticancer, and antimicrobial attributes. However, only monometallic nanoparticles combined with essential oils have been reported on so far with limited data. Bi- and tri-metallic nanoparticles have attracted immense attention because of their diverse sizes, shapes, high surface-to-volume ratios, activities, physical and chemical stability, and greater degree of selectivity. Combination therapy is currently blooming and represents a potential area that requires greater attention and is worthy of future investigations. This review summarizes the synergistic effects of essential oils with other antimicrobial combinations such as mono-, bi-, and tri-metallic nanocomposites. Thus, the various aspects of this comprehensive review may prove useful in the development of new and alternative therapeutics against antibiotic resistant pathogens in the future.

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Preparation, Characterization, and Antibacterial Effects of Chitosan Nanoparticles Embedded with Essential Oils Synthesized in an Ionic Liquid Containing System

Cited by 46 publications

References 37 publications

Synthesis of gold nanoparticles derived from mannosylerythritol lipid and evaluation of their bioactivities

Synthesis of gold nanoparticles derived from mannosylerythritol lipid and evaluation of their bioactivities

Contributions of Glycolipid Biosurfactants and Glycolipid-Modified Materials to Antimicrobial Strategy: A Review

Essential Oils and Mono/bi/tri-Metallic Nanocomposites as Alternative Sources of Antimicrobial Agents to Combat Multidrug-Resistant Pathogenic Microorganisms: An Overview

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