Preparation and transformations of steroidal butadiynes

3(2H)-Furanone as a promising scaffold for the synthesis of novel fluorescent organic dyes: an experimental and theoretical investigation

“…13 C NMR spectra were recorded on a 100.4 MHz Bruker spectrometer (Bruker Corp., UK) and the multiplicities of 13 C NMR resonances were determined by DEPT (90,135) experiments. The purity of the synthesised compounds was checked by TLC and analyses were carried out on 0.25 mm thick precoated silica plates (Merck Fertigplatten kieselgel 60F254).…”

“…The structures of products 1-3b were characterized by spectroscopic methods ( 1 H NMR, 13 C NMR, IR, ESI-MS and HRMS). Both compounds were isolated and purified by column chromatography on silica gel with high purity.…”

“…[13][14][15][16][17][18][19][20][21] Although a number of synthetic approaches for 3(2H)-furanones were known they were in many cases limited to specific substitution patterns. [13][14][15][16][17][18][19][20][21] Although a number of synthetic approaches for 3(2H)-furanones were known they were in many cases limited to specific substitution patterns.…”

“…Synthetic approaches to the 3(2H)-furanone ring system which vary in their degree of flexibility have appeared in the literature. [13][14][15][16][17][18][19][20][21] Although a number of synthetic approaches for 3(2H)-furanones were known they were in many cases limited to specific substitution patterns. The development of alternative strategies for the preparation of these heterocyclic compounds is therefore of considerable importance and continues to be a challenge.…”

IRMS detection of testosterone manipulated with 13C labeled standards in human urine by removing the labeled 13C

“…The reference compounds of 17-oxo-2,3-seco-5a-androstane-2,3-dioic acid and A-nor-5a-androstane-2,17-dione (ANAD) were synthesized [15,16] and their structures were confirmed by mass spectrometry and nuclear magnetic resonance (for details, see Supplementary data).…”