Preparation and release behavior of poly(methyl methacrylate-co-methacrylic acid)-based electrospun nanofibrous mats loaded with doxorubicin

Electrospun Membrane Based on Poly(L-co-D,L lactic acid) and Natural Rubber Containing Copaiba Oil Designed as a Dressing with Antimicrobial Properties

“…In their studies, Scaffaro et al (2017) [29] pointed out that mathematical models used to describe drug release have limitations in predicting the "burst release" effect. In this sense, and corroborating the results of Scaffaro et al (2017) [29] and López-Muñoz et al (2022) [30], the release data were fitted to mathematical models and divided into two-time intervals, corresponding to the two release phases. Thus, it was observed that the separate modeling of the two-time intervals fitted effectively to the power law model.…”

“…where M t = amount of released CO at an arbitrary time t; M ∞ = initial amount of CO added to the electrospun sample; k = release rate constant; and n suggests the nature of the release mechanism. Furthermore, the Higuchi model was also applied (Equation ( 3)) [30]:…”

Advanced applications of smart electrospun nanofibers in cancer therapy: With insight into material capabilities and electrospinning parameters

“…The in-vitro release features of DOX exhibited a reduced release rate of around 12% after 72 h for the synthesized copolymer, in contrast to the 44% release observed from the ES100 copolymer. Both copolymers exhibited a diffusion-controlled mechanism with two stages following Fick's second law ( López-Muñoz et al, 2023 ). Due to the particular characteristics of Eudragits, their most common use as nanofibers in cancer treatment is related to gastrointestinal cancers.…”