Preparation and Properties of Derivatives of Inositol^*

Abstract

Derivatives of Inositol 2397Reaction with Ammonia.-/3-Sulfopropionic anhydride was added in small portions to a large excess of liquid ammonia. After removal of the ammonia by evaporation, the white crystalline material was warmed gently to 60°t o remove the last traces of ammonia and crystallized from 80% methanol. The crystallized product melted at 179°. It was identified as the ammonium salt of ß-sulfopropionamide by its reactions and analysis. Anal.Caled, for C3H10C>4H2S (NH4+-03SCH2CH2-CONH2): N, 16.45. Found: N, 16.50. Reaction with Methyl Alcohol.-/3-Sulfopropionic anhydride was treated with a slight excess of anhydrous methanol and the excess then removed in a vacuum desiccator over phosphorus pentoxide. A crystalline highly hygroscopic material was obtained. The melting point of this substance was 73 °.

Recent Advances on Anilato-Based Molecular Materials with Magnetic and/or Conducting Properties

“…In fact, most of the attempts to obtain single crystals from a mixture of the (n-Bu 4 )N + salts of the [M III (X 2 An) 3 ] 3− precursors and Mn(II) chloride, yielded poorly crystalline products and only the crystal structure for the [(n-Bu) 4 O (19) are isostructural and show a layered structure with alternating cationic and anionic layers ( Figure 9). The only differences, besides the change of Cl 2 An 2− (17) with Br 2 An 2− (18), or Cr(III) (18) with Fe(III) (19), are (i) the presence of an inversion center in 18 and 19 (not present in 17) resulting in a statistical distribution of the M(III) and Mn(II) ions in the anionic layers; (ii) the presence of a water molecule coordinated to the Mn(II) ions in 16 (Mn-O1w 2.38(1) Å), in contrast with compounds 18 and 19 where this water molecule is not directly coordinated.…”

The crystal structure of tetrahydroxy-p-benzoquinone

“…Tetrahydroxy-p-benzoquinone (THQ), C6(OH)402, is one of a series of labile oxidation products of inositol which have interested organic and structural chemists for many years. Until recently the standard method for their preparation was to treat inositol with fuming nitric acid, a reaction difficult to control (Gelormini & Artz, 1930;Hoglan & Bartow, 1940;Preisler & Berger, 1942). The reaction leads to a mixture of products difficult to separate, and the individual products in some instances are so reactive toward oxygen that the dissolved oxygen in solvents makes recrystallization difficult or impossible.…”

The Fermentation of Inositol by Propionibacterium Pentosaceum

“…This brought to mind the products produced by the nitric acid oxidation of inositol. The series of reactions for the nitric acid oxidation of inositol has been worked out by Hoglan and Bartow (1940) and Gelormini and Artz (1930) and is listed in figure 1. From the chemical configuration it can be deduced that several of the compounds such as tetrahydroxyquinone and rhodizonic acid are pigments.…”

“…From the chemical configuration it can be deduced that several of the compounds such as tetrahydroxyquinone and rhodizonic acid are pigments. In order to demonstrate whether or not the unknown acid from inositol fermentation was one of the compounds of this series, tetrahydroxyquinone was synthesized according to the method of Hoglan and Bartow (1940). This highly pigmented compound which acts as a dibasic acid was found to be chromatographically identical to the major unknown component of the inositol fermentation.…”