Preparation and Characterization of Suvarna Bhasma Parada Marit

Abstract

Objectives:The goal of this study was to characterize Suvarna Bhasma Parada Marit by using the Ayurvedic test parameters, physico-chemical tests, and various instrumentation techniques.Methods:Suvarna Bhasma, an Ayurvedic formulation manufactured as per Bharat Bhaishajya Ratnakar 5/8357 (BBR), has been studied using various instrumentation techniques: X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDAX), laser particle size distribution (PSD) analysis, fourier transform infrared spectroscopy (FT-IR), and atomic absorption spectroscopy (AAS), and physico-chemical parameters, such as the loss on drying (LOD), loss on ignition (LOI), and acid insoluble Ash (AIA) were determined. In addition, Ayurvedic tests, such as Rekhapurnatva (enterable in the furrows of the fingers), Varitaratwa (floatable over water), Nirdhoomta (smokeless), Dantagre Kach-Kach (gritty particle feeling between the teeth), were performed.Results:The XRD study showed Suvarna Bhasma to be crystalline in nature and to contain more than 98% gold. The mean size of the gold crystallites was less than 10 microns, and the morphology was globular and irregular. Suvarna Bhasma contains gold as its single and major element, with EDAX and FT-IR spectra showing that it is more than 98% pure gold. The moisture content (LOD) is less than 0.5%, the LOI is less than 2%, and the AIA is not less than 95%. The Ayurvedic tests, as specified above, helped to confirm the quality of Suvarna bhasma prepared as per the text reference (BBR).Conclusion:This chemical characterization of Suvarna Bhasma performed in this study by using modern instrumentation techniques will be helpful in understanding its pharmacological actions and will help in establishing quality protocols and specifications to substantiate the safety, efficacy & quality of Suvarna Bhasma.

Chemical Compositions of Metals in Bhasmas and Tibetan Zuotai Are a Major Determinant of Their Therapeutic Effects and Toxicity

“…Characterizing the physicochemical properties of Bhasmas and/or Zoutai in herbo-metallic preparations is a prerequisite in uncovering the mysteries of these ancient remedies. For example, Suvarna Bhasma Parada Maritwas characterized by XRD, SEM, energy dispersive X-ray analysis (EDAX), laser particle size distribution (PSD) analysis, FTIR, atomic absorption spectroscopy (AAS), and physicochemical parameters, such as the loss on drying (LOD), loss on ignition (LOI), and acid insoluble ash (AIA) [ 41 ]. Shodhana procedure leads in the formation of bonds between surface particles of Tamra and Shodhana media by Fourier transform infrared (FTIR) spectroscopy [ 42 ].…”

To study the concept of ‘suvarnprashan sanskar ‘and its role in today’s era

“…Later on as meteorology developed, metals are used as a medicine after purifying them with herbs and its 'nano' form which will be more absorbable in body is prepared in the form of 'bhasma'. 10 There are many literatures available for the procedure of suvarn bhasma preparation, 7,8 out of which the procedure described in Bharat Bhaishaja Ratnakar is widely used.…”

“…Any form of gold, which is having better bioavailability should be the first choice for internal administration. 10 The bioavailability of all the forms of gold is yet to be established. A few related study reports are cited below.…”

“…Swarna Bhasma is said to have nanoparticles of gold which comprises gold-containing particles that are globular and have an average size of 56-57 nm. 10 In blood compatibility study, it was found that Swarna Bhasma contained gold nanoparticles with crystallite size 28-35 nm and was 90% pure gold. Another study found that colloidal gold uptake in gastrointestinal tract is dependent on particle size that is, smaller particles cross the gastrointestinal tract more readily.…”

“…11 For my study I used suvarnabhasma of Dhootpapeshwar Company, which is prepared with procedure described in bharat bhaishajya ratnakar and carried out a scientific study to prove its bioavailability. 10 With this I used brahmi ghruta and kalyanak ghruta and honey of fonda Ghat Company. For my study 140 children (bala) from the age of 1 month up to 16 years are selected in shree panchakarma and beauty clinic.…”