Preparation and characterization of silk fibroin/chitosan composite sponges for tissue engineering

Sionkowska, Alina; Płanecka, Anna

doi:10.1016/j.molliq.2012.10.042

Cited by 120 publications

(92 citation statements)

References 31 publications

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“…34 Having sufficient mechanical integrity to resist handling during implantation and in vivo loading is a requisite for scaffolding materials. 28 It has been reported that kidney 35 and liver 36,37 tissues have the maximum stress of 9.0 and 9.82 MPa, respectively. The PVA sponge fabricated in this study presented a maximum stress of 9.79 MPa, therefore, …”

Section: R E T R a C T E Dmentioning

confidence: 99%

RETRACTED: Fabrication and mechanical characterization of a polyvinyl alcohol sponge for tissue engineering applications

2013

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Polyvinyl alcohol (PVA) sponges are widely used for clinical applications, including ophthalmic surgical treatments, wound healing and tissue engineering. There is, however, a lack of sufficient data on the mechanical properties of PVA sponges. In this study, a biomechanical method is used to characterize the elastic modulus, maximum stress and strain as well as the swelling ratio of a fabricated PVA sponge (P-sponge) and it is compared with two commercially available PVA sponges (CENEFOM and EYETEC). The results indicate that the elastic modulus of the P-sponge is 5.32% and 13.45% lower than that of the CENEFOM and EYETEC sponges, while it bears 4.11% more and 10.37% less stress compared to the CENEFOM and EYETEC sponges, respectively. The P-sponge shows a maximum strain of 32% more than the EYETEC sponge as well as a 26.78% higher swelling ratio, which is a significantly higher absorbency compared to the CENEFOM. It is believed that the results of this study would help for a better understanding of the extension, rupture and swelling mechanism of PVA sponges, which could lead to crucial improvement in the design and application of PVAbased materials in ophthalmic and plastic surgeries as well as wound healing and tissue engineering.

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Section: R E T R a C T E Dmentioning

confidence: 99%

RETRACTED: Fabrication and mechanical characterization of a polyvinyl alcohol sponge for tissue engineering applications

2013

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“…After γ-irradiation (No. 5,6,7,8,9,13,16), the typical of homogineous film with rough surface structure with low density fibroin chains was observed. This results were expected the large surface area and pore volum.…”

Section: Resultsmentioning

confidence: 89%

Preparation of cross-linked silk fibroin film by γ-irradiation and their application as supports for human cell culture

Park¹,

Kim²,

Choi³

2014

Analytical Science and Technology

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This study described about preparation of the cross-linked silk fibroin (SF) film by γ-irradiation of the casted SF film, which is fabricated from aqueous solution regenerated via fibers of cocoons and their application as supports for human cell culture. The properties of cross-linked SF film were evaluated by FT-IR spectroscopy, contact angle, solubility to water, thermal analysis, surface area analyzer, and morphology via scanning electron microscopy (SEM). The cross-linked SF films were not dissolved in water and exhibited the rough surface morphology, large surface area, and good thermal properties. The human fibroblast cell (CCD986sk) and embryo kidney-ft cell were well growed on the surface of cross-linked SF film supports prepared by γ-irradiation. The cross-linked SF film prepared by γ-irradiation can be used as biomaterials for human cell culture.

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“…Silk fibroin has been also investigated for many other biomedical applications, including osteoblast, hepatocyte and fibroblast cell support matrixes, as well as for ligament tissue engineering [17], urologic tissue engineering and functional tissue engineering of the corneal epithelium [18,19]. Moreover, cells, antibiotics, monoclonal antibodies and peptides have been encapsulated in silk using various processing approaches and material formats [20].…”

Section: Silk Fibre Proteinsmentioning

confidence: 99%

The Mulberry Silkworm—A New Source of Bioactive Proteins

Łochyńska¹

2015

JAST-A

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Abstract:Beyond the commonly known proteins built silk fibres-fibroin and sericin, there are almost 300 bioactive proteins in the silkworm haemolymph. The aim of this work was to present bioactive compounds obtained from the silk fibre and isolated from the body of this insect, which may be used in medical and pharmacological applications. The most important are bioactive proteins. However, the juvenile stages of mulberry silkworm possess other very valuable active substances.

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Preparation and characterization of silk fibroin/chitosan composite sponges for tissue engineering

Cited by 120 publications

References 31 publications

RETRACTED: Fabrication and mechanical characterization of a polyvinyl alcohol sponge for tissue engineering applications

RETRACTED: Fabrication and mechanical characterization of a polyvinyl alcohol sponge for tissue engineering applications

Preparation of cross-linked silk fibroin film by γ-irradiation and their application as supports for human cell culture

The Mulberry Silkworm—A New Source of Bioactive Proteins

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