Preparation and Characterization of Poly(lactic acid) Micro- and Nanofibers Fabricated by Centrifugal Spinning

Comparative Investigation of Electrospun and Centrifugal Spun Polylactic Acid for Filtration Performance and Reusability

“…CS PLA fibers, produced at concentrations of 10, 13, and 16 wt %, exhibit mostly bead-free morphology (see Supporting Figure S3 for representative SEMs of CS PLAs at PLA concentrations and RPM used), with the exception of 3000 rpm at 10 wt % leading to the formation of minimal beads and fibers (see Table ). Consistent with existing literature, ,,,, the morphology of nanofibers was influenced by the concentration of the polymer solution and rotational speed of the spinneret. Increasing the rotational speed at a given PLA concentration generally resulted in smaller fiber diameter, presumably due to the higher centrifugal forces (see Figure a); previous PLA ES and CS studies observed an augmentation of the degree of crystallinity due to the higher extensional force. − The fiber diameter distribution in CS PLA ranges from 40% (all of 10 wt % CS PLA samples) to 100% (all of 16 wt % CS PLA samples) of the mean fiber diameter, which is wider than typical ES fibers with a standard deviation of 10–20% .…”

“…Increasing the rotational speed at a given PLA concentration generally resulted in smaller fiber diameter, presumably due to the higher centrifugal forces (see Figure a); previous PLA ES and CS studies observed an augmentation of the degree of crystallinity due to the higher extensional force. − The fiber diameter distribution in CS PLA ranges from 40% (all of 10 wt % CS PLA samples) to 100% (all of 16 wt % CS PLA samples) of the mean fiber diameter, which is wider than typical ES fibers with a standard deviation of 10–20% . The wider distribution of CS diameters within a sample is also in line with previous literature studies. ,,,, As displayed in Figure a,b, the diameter distribution gets wider as PLA concentration increases; this trend is attributable to increased solution viscosity resisting extensional strain from the rotational force.…”

“…Such performance is comparable to commercial 3 M N95 masks yet much lighter in weight . Several studies demonstrated that PLA could be spun into nanofibers via centrifugal spinning ,,, as well; the fiber morphology was found to be influenced by several factors, including the concentration of the polymer solution, rotational speed of the spinneret, and choice of solvents. ,,,, …”

“…29 Several studies demonstrated that PLA could be spun into nanofibers via centrifugal spinning 2,30,33,38 as well; the fiber morphology was found to be influenced by several factors, including the concentration of the polymer solution, rotational speed of the spinneret, and choice of solvents. 2,30,33,38,39 Although PLA nanofibers can be fabricated through both electrospinning and centrifugal spinning, there is currently a lack of research on the filtration performance and reusability of centrifugally spun PLA, particularly in relation to fiber morphology. Additionally, a direct comparison between centrifugal spinning and electrospinning regarding filtration performance and reusability has not been conducted.…”

Engineering and Evaluation of Forcespun Gelatin Nanofibers as an Isorhamnetin Glycosides Delivery System

“…Forcespinning™ (FS) or the centrifugal spinning method has emerged as a novel strategy for the fabrication of nanofibers, and this method uses centrifugal force to form ultrafine nanofibers (from 25 nm to several µm) [35]. Unlike E-spinning, the FS method consists of ejecting a polymer solution through thin needles which rotate at high-speed conditions, thus the centrifugal force produces solidification, and the stretching of the polymer and the evaporation of the solvent, allowing for the collection of the nanofibers on the walls of a cylindrical collector [36,37]. Since it uses centrifugal forces instead of electric fields, the FS method provides a higher productivity rate, over 1 mL/min per nozzle, around 200 times higher than E-spinning [35].…”