Preparation and characterization of oxidized pectin/N-succinyl chitosan/graphene oxide hydrogels

Self-healing, injectable chitosan-based hydrogels: structure, properties and biological applications

“…This method of periodate-mediated formation of aldehyde group was utilized in polysaccharides like gum Arabic, 51,52 alginate, [53][54][55] chondroitin sulfate, 29,[56][57][58] dextran, 30,59-61 hyaluronic acid, 31,[62][63][64][65] pectin. [66][67][68][69] In the second strategy, the polysaccharide is generated so that aldehyde groups are present on the ends of the linear polymers as the crosslinking agent. 50,70 Small dialdehyde molecules serve as the best crosslinking agents for this strategy, but their toxicity limits its application.…”

“…Chitosan can be blended with other polysaccharides of the same or different family depending on the degree of miscibility and number of polymer chains as another strategy. Alginate, 34,55 cellulose, 35,38,67,79,80 and gelatin, 55 with the help of chemical oxidation, convert the hydroxy groups into aldehyde bonds. This combination of blending of various polysaccharides with chitosan enhances the functional, mechanical, and self-healing ability of chitosan (Fig.…”