Preparation and characterization of a Bacterial cellulose/Chitosan composite for potential biomedical application

Kim, Jaehwan; Cai, Zengxuan; Lee, Hyun Sook; Choi, Gwang Seong; Lee, Don Haeng; Jo, Chul H.

doi:10.1007/s10965-010-9470-9

Cited by 182 publications

(101 citation statements)

References 16 publications

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“…A sharp characteristic peak of O-H stretching appears at 3347 cm −1 and another important peak of 1645 cm −1 is assigned to the glucose carbonyl stretching [38,39]. A series of bands from 1200 to 1000 cm −1 are related to the stretching of C-O-C of sugar rings and C-O stretching vibrations of the primary (C 6 ) and secondary hydroxyl (C 2 , C 3 ) groups.…”

Section: Ftir-atr Analysismentioning

confidence: 99%

Novel Bionanocellulose/κ-Carrageenan Composites for Tissue Engineering

et al. 2018

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Featured Application: Bionanocellulose/κ-carrageenan composites developed within this study meet the specific tissue engineering requirements, including high tensile and compression strength, water holding capacity, and water retention ratio, suitable swelling properties as well as the positive effect on cell differentiation. As the key properties of these composites may be easily modified during their fabrication, the established procedure may lead to the production of customized scaffolds.Abstract: In this work, novel bacterial cellulose/κ-carrageenan (BNC/κ-Car) composites, being potential scaffolds for tissue engineering (TE), and outperforming the two polymers when used as scaffolds separately, were for the first time obtained using an in situ method, based on the stationary culture of bacteria Komagateibacter xylinus E25. The composites were compared with native BNC in terms of the morphology of fibers, chemical composition, crystallinity, tensile and compression strength, water holding capacity, water retention ratio and swelling properties. Murine chondrogenic ATDC5 cells were applied to assess the utility of the BNC/κ-Car composites as potential scaffolds. The impact of the composites on the cells viability, chondrogenic differentiation, and expression patterns of Col1α1, Col2α1, Runx2, and Sox9, which are indicative of ATDC5 chondrogenic differentiation, was determined. None of the composites obtained in this study caused the chondrocyte hypertrophy. All of them supported the differentiation of ATDC5 cells to more chondrogenic phenotype.

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Section: Ftir-atr Analysismentioning

confidence: 99%

Novel Bionanocellulose/κ-Carrageenan Composites for Tissue Engineering

et al. 2018

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“…The structural features, specifically the fibril arrangement, provide an excellent scenario for the use of BC in the synthesis of various composites. In fact, BC can be used as both a matrix and a reinforcement material for composite design [21,27,95,96]. A number of BC composites have already been produced to overcome the inadequacies and enhance the physiological, biological, chemical, and mechanical features of BC [19, 20, 27-29, 43, 96-98].…”

Section: Bc Compositesmentioning

confidence: 99%

“…Among these schemes, the initial addition of materials to BC culture media (in situ addition), the treatment of BC with solutions and suspensions (ex situ addition), and the dissolution of BC in solvents with consequent blending are the most commonly used techniques [21]. It has been observed that BC composites have high levels of antibacterial, antifungal, antiviral, biocompatible, wound healing, conductive, magnetic, and optical properties [19,[27][28][29].…”

Section: Introductionmentioning

confidence: 99%

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Synthesis, Chemistry, and Medical Application of Bacterial Cellulose Nanocomposites

Ul-Islam

Khan

Khattak

et al. 2015

Advanced Structured Materials

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Bacterial cellulose (BC), an environmental friendly polymeric material, has recently received immense attention in the human society. Herein, we have focused on the biosynthesis, chemical structure, and physiological behavior of BC along with synthetic routes and medical applications of its nanocomposites. The structure of BC consists of nanofibrils made up of (1 → 4) β-glycosidic linked glucose units interconnected through intra-and intermolecular hydrogen bonds. The interconnected 3D network structure of BC nanofibers with a high degree of nanoporosity makes BC an ideal candidate for the incorporation of nanomaterials to form reinforced composites. BC nanocomposites have been synthesized through a number of routes that have not only improved the existing properties of BC, but also enhanced it with novel features. Among nanomaterials, metal, metal oxides, and organic nanomaterials have been effectively used to engender antimicrobial, biocompatible, conductive, and magnetic properties in BC. BC nanocomposites have been successfully employed in the medical field and have shown a high clinical value for wound healing and skin tissue repair. Recent interest has been focused on designing ideal biomedical devices like artificial skin and artificial blood vessels from BC. This study will provide an extensive background about the primary features of BC and discuss the synthetic routes and chemical feasibility of BC nanocomposites along with their current and future application in the medical field.

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“…For instance, Bodin et al (2007b) had introduced specific peptide sequence to BC nano-fibrils for the sake of improving cell attachment and proliferation. Kim et al (2011) prepared a BC/chitosan composite for potential biomedical application. Growth factor has been introduced on biodegradability and biocompatibility of macroporous BC by Lin et al (2011).…”

Section: Introductionmentioning

confidence: 99%