Preparation and antioxidant activity of selenium nanoparticles decorated by polysaccharides from Sargassum fusiforme

Abstract

In this study, the response surface method was employed to optimize the extraction conditions of the ultrasonic‐assisted extraction of Sargassum fusiforme polysaccharides (SFPS). The effects of four independent variables (hot water extraction time, ultrasonic time, ultrasonic power, and material‐to‐liquid ratio) on the extraction rate of SFPS were tested. In addition, the SFPS functionalized nanoselenium (SFPS‐SeNPs) was prepared by chemical reduction method, whose characterization and in vitro antioxidant activity were investigated. The results showed that the yield of the crude SFPS was 25.8% at the optimal conditions of material‐to‐liquid ratio 1:50 (w/v), ultrasonic power 200 W, ultrasonic time 15 min, and water bath time 130 min. A series of characterization experiments showed that the SFPS‐SeNPs performed higher dispersion and stability than naked SeNPs. Furthermore, the in vitro antioxidant activity assay indicated that SFPS functioned as a modifier improved the free radical scavenging activity of SeNPs significantly. In conclusion, this study provided a method to extract SFPS as a carrier for SeNPs, and SFPS‐SeNPs could not only improve the stability of SeNPs, but also exerted the biological activities of SFPS. Practical Application This research provided new ideas for the application of SFPS and the development of nanoselenium preparation carriers.

Construction of Polygonatum sibiricum Polysaccharide Functionalized Selenium Nanoparticles for the Enhancement of Stability and Antioxidant Activity

“…The assay of ABTS radical cation scavenging ability was performed as described previously with some modification [ 28 ]. ABTS and potassium persulfate (K 2 S 2 O 8 ) were dissolved in distilled water.…”

Preparation, Characterization, and Antioxidant Properties of Phycocyanin Complexes Based on Sodium Alginate and Lysozyme

“…The ABTS free radical scavenging assay was modified from the method reported in the literature ( 20 ). ABTS (14 mmol/L) was mixed with K 2 S 2 O 8 (4.9 mmol/L) in equal volumes and kept away from light at room temperature for 12 h to obtain ABTS radical assay solution.…”

Pilot study of toxicological safety evaluation in acute and 28‐day studies of selenium nanoparticles decorated by polysaccharides from Sargassum fusiforme in Kunming mice

“…The dried S. fusiforme used in the experiment was purchased from Wenzhou Jiahai Food Company Limited (Dongtou County, Zhejiang, China) and SFPS was prepared and characterized in our lab (Wang et al., 2021). A 4% paraformaldehyde fixative was obtained from Biosharp (Hefei, Anhui, China), and other reagents were purchased from Sigma‐Aldrich (St Louis, MO, USA).…”

“…We previously reported that SeNPs decorated by polysaccharides from Sargassum fusiforme (SFPS‐SeNPs) have some antioxidant activity (Wang et al., 2021). Polysaccharides from Sargassum fusiforme (SFPS) are a suitable template to make stable SeNPs and control particle size of nanoparticles.…”