Preparation and antifouling property of polyurethane film modified by chondroitin sulfate

Yuan, Huatang; Xue, Junqing; Qian, Bin; Chen, Huaying; Zhu, Yonggang; Lan, Minbo

doi:10.1016/j.apsusc.2016.10.083

Cited by 24 publications

(18 citation statements)

References 60 publications

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“…Furthermore, there were indications that coating of ureteral stents with glucosaminoglycans [21] or heparin [22] (both negatively charged) resulted in decreased biofilm formation and encrustations. Our comparative analyses showed that the low quantity of encrustation could be correlated with a strong negative surface charge and good hydrophilicity of the polymer (Group 2).…”

Section: Surface Characteristics Can Be Correlated To Encrustation Massmentioning

confidence: 99%

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Prevention of Encrustation on Ureteral Stents: Which Surface Parameters Provide Guidance for the Development of Novel Stent Materials?

Rebl

Renner²,

Kram

et al. 2020

Polymers

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Encrustations of ureteral stents are one of the biggest problems with urological implants. Crystalline biofilms can occur alone or in combination with bacterial biofilms. To identify which surface parameters provide guidance for the development of novel stent materials, we used an in vitro encrustation system. Synthetic urine with increasing pH to simulate an infection situation was pumped over the polymer samples with adjusted flow rates at 37 °C to mimic the native body urine flow. Chemical surface features (contact angle, surface charge), as well as encrustations were characterized. The encrustations on the materials were analyzed quantitatively (dry mass) and qualitatively using scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), and Fourier transform infrared spectroscopy (FTIR). The aim of this comparative study was to identify crucial surface parameters that might predict the quantity and type of mineral deposits in vitro and provide guidance for the development and screening of new polymer-based biomaterials for ureteral stent design. For the first time, we could identify that, within the range of our polymers, those materials with a slight hydrophilicity and a strong negative zeta potential (around −60 mV) were most favorable for use as ureteral stent materials, as the deposition of crystalline biofilms was minimized.

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Section: Surface Characteristics Can Be Correlated To Encrustation Massmentioning

confidence: 99%

Section: Surface Characteristics Can Be Correlated To Encrustation Massmentioning

confidence: 99%

Prevention of Encrustation on Ureteral Stents: Which Surface Parameters Provide Guidance for the Development of Novel Stent Materials?

Rebl

Renner²,

Kram

et al. 2020

Polymers

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“…A general approach to friction reduction is thus an increase in the surface hydrophilicity of polyurethanes through coating or surface chemical modi cation [45]. Surface characterisation methods for such materials include coe cient of friction measurements, typically applying the ASTM D1894-14 standard method [46], contact angle measurements [47,48], X-ray photoelectron spectroscopy [47], secondary ion mass spectrometry [49], scanning electron microscopy [48] and atomic force spectroscopy [47]. When a medical device is in contact with a bodily uid such as blood, the rst thing that occurs on the surface is protein adsorption, which can be determined with the use of quartz crystal microbalance [50] and iodination radiolabelling [51].…”

Section: Surface Characterisation Techniques In the Development Of Bimentioning

confidence: 99%

Polyurethanes for Medical Use

Pivec

Smole

Gašparič

et al. 2017

TEK

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Polyurethanes are synthetic copolymers containing urethane linkages in their complex chemical structure. They consist of three monomers: a diisocyanate, a polyol and a chain extender, which enables the synthesis of an endless number of polyurethanes with diff erent physicochemical and mechanical properties. The physicochemical properties of various polyurethanes are largely dependent on the conformation of polyols, which may contain two or more diff erent polyols, stabilisers, catalysts, liquids or solid additives and, in the case of foams, foaming agents. Depending on the structure of the polyols, i.e. the length of the chain, structure of the units (aliphatic or aromatic), ester or ether groups, or functionalisation by hydroxyl groups, polyurethanes may be fl exible or rigid, and therefore suitable for various applications. In addition to the physical and chemical structure of polyurethanes, this review paper specifi cally addresses their use in medicine, particularly in wound dressings, tissue engineering scaff olds and drug delivery with nanoparticles and nanocapsules, and provides guidelines for the development of new biodegradable polyurethane materials.

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“…This naturally occurring glycosaminoglycan (GAG) is an anionic polyelectrolyte. It has garnered much attention in recent years because of its promising properties, such as non-toxicity, biocompatibility, anti-inflammatory activity [30,31], and its potential as an antibacterial and antiviral agent [32]. In addition, the broad spectrum of the biological activities of ChS suggests a potential benefit to the biomedical field, for example, in osteoarthritis, interstitial cystitis and urinary tract infection treatments, cartilage tissue engineering [31], as dietary supplement, in the drug delivery systems [30,33], and in the development of orthopedic materials.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Activity and Cytotoxicity of Immobilized Glucosamine/Chondroitin Sulfate on Polylactic Acid Films

et al. 2019

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Polylactic acid (PLA) is one of the most produced polymeric materials, due to its exceptional chemical and mechanical properties. Some of them, such as biodegradability and biocompatibility, make them attractive for biomedical applications. Conversely, the major drawback of PLA in the biomedical field is their vulnerability to bacterial contamination. This study focuses on the immobilization of saccharides onto the PLA surface by a multistep approach, with the aim of providing antibacterial features and evaluting the synergistic effect of these saccharides. In this approach, after poly (acrylic acid) (PAA) brushes attached non-covalently to the PLA surface via plasma post-irradiation grafting technique, immobilization of glucosamine (GlcN) and chondroitin sulfate (ChS) to the PAA brushes was carried out. To understand the changes in surface properties, such as chemical composition, surface topography and hydrophilicity, the untreated and treated PLA films were analyzed using various characterization techniques (contact angle, scanning electron microscopy, X-ray photoelectron spectroscopy). In vitro cytotoxicity assays were investigated by the methyl tetrazolium test. The antibacterial activity of the PLA samples was tested against Escherichia coli and Staphylococcus aureus bacteria strains. Plasma-treated films immobilized with ChS and GlcN, separately and in combination, demonstrated bactericidal effect against the both bacteria strains and also the results revealed that the combination has no synergistic effect on antibacterial action.

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Preparation and antifouling property of polyurethane film modified by chondroitin sulfate

Cited by 24 publications

References 60 publications

Prevention of Encrustation on Ureteral Stents: Which Surface Parameters Provide Guidance for the Development of Novel Stent Materials?

Prevention of Encrustation on Ureteral Stents: Which Surface Parameters Provide Guidance for the Development of Novel Stent Materials?

Polyurethanes for Medical Use

Antibacterial Activity and Cytotoxicity of Immobilized Glucosamine/Chondroitin Sulfate on Polylactic Acid Films

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