Preparation and analysis of heart and skeletal muscle specimens with LAMMA

Lyophilization: a useful approach to the automation of analytical processes?

“…Metal traces and subtraces have so far been the most frequently determined inorganic compounds in biological samples, both in solid [55][56][57][58][59][60][61][62][63][64][65][66] and in liquid [67][68][69] materials by radiochemical [55-57, 64-67], X-ray [61, 62,69, 70] and atomic absorption spectrometric techniques [68].…”

“…Even so, 92% of the total amount of Pb was retained in the procedure. In another freezing-drying approach, the ratio of the freezing damage in the tissue samples to the formation of ice crystals and intracellular K/Na was measured [60]. A substantially decreased ratio was obtained.…”