Preoperative Tumor Embolization

Ashour, Ramsey; Aziz-Sultan, Ali

doi:10.1016/j.nec.2014.04.015

Cited by 48 publications

(24 citation statements)

References 12 publications

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“…Tumor embolization is occasionally used before tumor resection to reduce intraoperative blood loss, which can be a major cause of surgery‐associated morbidity. This technique is often used if the tumor has signs of hypervascularity or the vasculature is difficult to access as long as the embolization procedure does not pose additional risk . There is also evidence showing that embolization may decrease the time of the operation.…”

Section: Surgerymentioning

confidence: 99%

“…This technique is often used if the tumor has signs of hypervascularity or the vasculature is difficult to access as long as the embolization procedure does not pose additional risk. 31 There is also evidence showing that embolization may decrease the time of the operation. A retrospective study of 46 patients with MESCC treated with preoperative embolization showed a significant reduction in intraoperative blood loss, 32 although a randomized, prospective study of 45 patients found the decrease in blood loss to be notable only in a subgroup analysis of hypervascular tumors.…”

Section: Surgerymentioning

confidence: 99%

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Diagnosis and treatment of epidural metastases

Yáñez

Miller

Batchelor

2016

Cancer

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Epidural metastases occur in 5% to 10% of cancer patients and represent a neurological emergency. Patients most commonly present with an acute onset of motor weakness, and restoration of neurological function is critically dependent on prompt diagnosis and treatment. This review discusses the clinical, epidemiological, and radiological features associated with epidural metastases and resulting spinal cord compression. Moreover, current treatment paradigms are reviewed. The timely initiation of radiation as well as surgery in select cases is critical for preserving neurological function and achieving local tumor control and pain control. Future studies investigating surgical and radiation treatment for metastatic epidural cord compression are urgently needed. Cancer 2017;123:1106-1114. © 2016 American Cancer Society.

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Section: Surgerymentioning

confidence: 99%

Section: Surgerymentioning

confidence: 99%

Diagnosis and treatment of epidural metastases

Yáñez

Miller

Batchelor

2016

Cancer

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“…The encouraging outcomes in assessing tumor‐supporting blood vessels in vivo highlighted the potential clinical application of vascular embolization and precise resection of tumors during surgery. Tumor vascular embolization or ligation leads to less complications and thus have many advantages over traditional surgery, particularly when open surgery is risky or inappropriate in certain situations . Therefore, we peered deeper into the feasibility of CQL intraoperatively to implement NIR‐II image‐navigated surgery of femur orthotopic osteosarcoma.…”

Section: Resultsmentioning

confidence: 99%

Monitoring the Real‐Time Circulatory System‐Related Physiological and Pathological Processes In Vivo Using a Multifunctional NIR‐II Probe

Liu

et al. 2019

Adv Funct Materials

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The dysfunction of the circulatory system leads to various pathological processes with high morbidity. Recently, fluorescence imaging in the nearinfrared II (NIR-II) window (1000-1700 nm) has attracted immense attention in many biological processes. The rapid metabolism and low toxicity of some NIR-II organic small molecules indicate their feasibility for use in visualizing the circulatory system. However, most of the reported NIR-II organic small molecules presently encounter such dilemmas as complicated synthetic procedures and low quantum yields (QY). To address this challenge, a series of facilely prepared NIR-II organic small molecule CQ-T (CQ-1-4T) are designed and these compounds are loaded with biocompatible human serum albumin (HSA) to improve QY. Among them, CQL (CQ-4T/HSA) demonstrates superior optical properties and a 6.65-fold increase in fluorescence compared to the small molecule alone. Further work validates the efficacy and accuracy of CQL in monitoring the real-time circulatory system-related physiological and pathological processes in vivo, including thrombosis, peripheral arterial disease, tumor angiogenesis, and lymphatic drainage. Moreover, the excellent optical properties of CQL enable precise tumor resection and sentinel lymph node biopsy under NIR-II navigation. In conclusion, CQL is a novel and promising NIR-II organic probe with multifunctional imaging capability. It is highly desirable to accelerate its future translations into the clinic.

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“…Preoperative embolization of meningiomas has been well described,16 18 with most operators employing particle (PVA, Embospheres) or liquid embolization agents (Onyx, NBCA) to achieve tumor devascularization 19. While it is widely accepted that tumor devascularization through endovascular embolization facilitates ease of tumor resection both through necrotic softening of the tumor (making it more ‘suckable’ intraoperatively) and reduced operative blood loss, only one prior study has demonstrated a statistically significant reduction in blood loss with preoperative embolization.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, NBCA tends to be more adherent to the microcatheter tip, resulting in an increased risk of microcatheter retention in instances of embolic agent reflux 19. In addition, Onyx may be deployed through microcatheters as small as 0.013 in.…”

Section: Discussionmentioning

confidence: 99%

Preoperative embolization of intracranial hemangiopericytomas: case series and introduction of the transtumoral embolization technique

Hanak

Haussen

Ambekar

et al. 2015

J NeuroIntervent Surg

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The extent of preoperative embolization of HPCs correlates with decreased intraoperative blood loss. However, HPCs with an ICA/VB-dominant blood supply remain challenging embolization targets, demonstrating reduced devascularization percentages compared with ECA-dominant counterparts. The authors favor the use of Onyx for ICA/VB-dominant HPCs, noting a trend towards an improved devascularization rate.

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Preoperative Tumor Embolization

Cited by 48 publications

References 12 publications

Diagnosis and treatment of epidural metastases

Diagnosis and treatment of epidural metastases

Monitoring the Real‐Time Circulatory System‐Related Physiological and Pathological Processes In Vivo Using a Multifunctional NIR‐II Probe

Preoperative embolization of intracranial hemangiopericytomas: case series and introduction of the transtumoral embolization technique

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