Preoperative Staging of Rectal Cancer by Magnetic Resonance Imaging Remains an Imprecise Tool†

Effectiveness of MRI for the Assessment of Mesorectal Fascia Involvement in Patients with Rectal Cancer: A Systematic Review and Meta-Analysis

“…Among the 14 studies, 2 did not have neo-ChRT and 12 did. All 14 studies used ≤1 mm as the definition of MRF+, but 3 of them [26,32,34] also used other definitions (≤2 and ≤5 mm). A total of 10 studies and 1,286 patients (636 of whom had neo-ChRT) were included when discussing the influence of neo-ChRT (table 2).…”

“…In the 14 included studies, only 6 [23,26,28,30,32,33] gave a positive instruction on whether metastatic lymph node was used for measuring the closest distance to MRF (table 1). This may be another limitation of our study.…”

Imaging of Tissue Elasticity in Gastrointestinal Disorders

“…Most rectal tumours are staged by MRI, but this method still lacks accuracy in staging rectal tumours B T2 (Bipat et al 2004;Tytherleigh et al 2008). Endo Rectal ultrasonography (ERUS) with elastography is feasible to perform during an outpatient consultation preoperatively, and yields good results in distinguishing malignant tumours from adenomas (Figs.…”

Predictors of tumor response after preoperative chemoradiotherapy for rectal adenocarcinomas

“…Some studies have confirmed that there can be differential responses between the primary tumor and the mesorectal lymph nodes [10,11]. Regarding literature, the proportion of lymph node metastasis in pCR seems low, with a median rate of 7% ranging from 2% to 11% [12].…”

“…The assessment of response to CRT is, for the most part, based on subjective clinical evaluation such as reduced tumor size, improved tumor mobility, or histopathologic criteria [8][9][10][11].…”