Preoperative predictors for allogenic blood transfusion in hip and knee arthroplasty for rheumatoid arthritis

Ogbemudia, Ann E.; Yee, Sze Y.; Macpherson, Gavin; Manson, Lynn; Breusch, Steffen

doi:10.1007/s00402-013-1784-8

Cited by 31 publications

(43 citation statements)

References 21 publications

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“…Ogbemudia et al investigated preoperative predictors of the need for transfusion in patients undergoing hip and knee arthroplasty (27). They showed that low preoperative Hb, total hip arthroplasty, previous history of myocardial infarction, and previous blood transfusion were significant predictors of the need for allogeneic blood transfusion in the recent procedure; however, their retrospective design restricts implication of their study findings.…”

Section: Discussionmentioning

confidence: 89%

Risk Factors for Blood Loss Following Total Knee Arthroplasty

Moghtadaei

Shahoseini

2014

Shafa Ortho J

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Background: Blood loss following total knee arthroplasty (TKA) is a challenging issue faced by orthopedic surgeons. Determination of risk factors for significant blood loss is a significant step toward blood management. Objectives: The aim of this study was to determine factors predicting intraoperative blood loss, postoperative drainage, and need to blood transfusion in patients undergoing TKA. Patients and Methods:In a prospective study, 96 consecutive patients who underwent primary cemented TKA were included. Intraoperative blood loss, postoperative blood drainage, and hemoglobin (Hb) drop were measured and analyzed in terms of age, sex, body mass index, and tourniquet closure time. Results: The mean age of patients was 68.4 ± 5.6 years (range, 52-75). Mean intraoperative blood loss and postoperative drainage were 147.1 ± 97.4 mL and 494.4 ± 188.1 mL, respectively. Based on a regression model, males and obese patients had significantly higher intraoperative blood loss (P < 0.05). Additionally, male sex and older age were significantly associated with more severe drop in Hb on the first postoperative day; however, there was no predictor of need for transfusion in regression analysis. Conclusions: Male sex and obesity were the risk factor for intraoperative blood loss while the elderly and male patients experienced more severe postoperative bleeding.

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Section: Discussionmentioning

confidence: 89%

Risk Factors for Blood Loss Following Total Knee Arthroplasty

Moghtadaei

Shahoseini

2014

Shafa Ortho J

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“…Tranexamic acid has been shown to effectively decrease blood loss and postoperative transfusion rates in orthopedic patients without an increase in TEE [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19]. Other studies investigating risk factors for postoperative transfusion found preoperative Hgb to be a significant predictor for subsequent packed red blood cell transfusion [23][24][25][26].…”

Section: Discussionmentioning

confidence: 99%

“…Many of these investigations demonstrated preoperative Hgb value to be a significant predictor of postoperative transfusion [23][24][25][26]. As such, there are certain preoperative Hgb levels where postoperative transfusion is less likely and the utility of TXA is unknown.…”

mentioning

confidence: 99%

Tranexamic Acid Benefits Total Joint Arthroplasty Patients Regardless of Preoperative Hemoglobin Value

Whiting

Duncan

Sierra

et al. 2015

The Journal of Arthroplasty

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While tranexamic acid (TXA) reduces transfusion in total joint arthroplasty (TJA), it remains unclear whether there is a preoperative hemoglobin (Hgb) threshold above which it is no longer beneficial. 2100 primary TJA patients were retrospectively categorized by preoperative Hgb; 1161 (55%) received TXA. Transfusion rates decreased with TXA in all groups; with Hgb>15 the transfusion rate was 0.5% with TXA and 4.5% without (P=0.0086); with Hgb>11 the transfusion rate was 4.7% with TXA and 18.7% without (P<0.0001). Patients receiving TXA had a shorter LOS by 0.51 days (P<0.0001). Patients receiving a postoperative transfusion had a longer LOS by 0.69 days (P<0.0001). TXA should be considered in all TJA patients independent of preoperative Hgb level.

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“…Although there are numerous studies of the role of patient and surgical factors on the amount of bone loss in TKA, they are not uniform in their conclusions (2,3). This has been commented by the authors.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors for Blood Loss Following Total Knee Arthroplasty: How Far is Left to Go?

Abolghasemian

2015

Shafa Ortho J

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Preoperative predictors for allogenic blood transfusion in hip and knee arthroplasty for rheumatoid arthritis

Abstract: The ability to identify those within this high-risk group who are likely to receive blood transfusion allows for an informed, appropriate and cost effective approach to blood management strategies.

Cited by 31 publications

References 21 publications

Risk Factors for Blood Loss Following Total Knee Arthroplasty

Risk Factors for Blood Loss Following Total Knee Arthroplasty

Tranexamic Acid Benefits Total Joint Arthroplasty Patients Regardless of Preoperative Hemoglobin Value

Risk Factors for Blood Loss Following Total Knee Arthroplasty: How Far is Left to Go?

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