“…Few studies included only locally or metastatic RCC patients (14,23), but most studies reported the inclusion of generalized RCC patients (12,13,15,21,22,24,25). Overall survival (OS) was reported in five studies (12)(13)(14)(15)23), cancer-specific survival (CSS) was assessed in six studies (14,(21)(22)(23)(24)(25), and progression-free survival (PFS) was evaluated in four studies (12,14,15,25). Finally, HRs and corresponding 95% CIs were sufficiently provided by all included studies.…”