Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia

Kil, Ho-Yeong; Kim, W.O.; Chung, Woung Youn; Kim, G.H.; Seo, Hye Jeong; Hong, Jeong-Yeon

doi:10.1093/bja/aer305

Cited by 133 publications

(102 citation statements)

References 28 publications

(16 reference statements)

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“…But the state anxiety (STAI-S), measured both in the waiting room ( Figure 2) and in the operating room just before induction (Figure 3), had no significant positive correlation with the Propofol dose requirement. This is in agreement with previous studies of Marantes et al 5 and Kil et al 6 On the other hand, heart rate (HR), which was measured in the operating room just before the induction (Figure 4), had strong positive correlation with the Propofol dose requirement for induction. We also observed that STAI-S measured in the operating room had a strong positive correlation with HR ( Figure 5).…”

Section: Discussionsupporting

confidence: 92%

“…5 Kil et al reported that, during the induction of anesthesia, patients with higher levels of both state and trait anxieties required greater amounts of propofol to reach light (85) and moderate levels (75) of sedation. 6 However, the amount of Propofol required to reach a deep level of sedation (BIS 65), was associated with higher levels of trait, but not state anxiety.…”

Section: Discussionmentioning

confidence: 99%

“…2,3 The studies have been conducted on different hypnotic drugs from methohexitone to propofol for the purpose to test the hypothesis of whether preoperative anxiety actually increases the requirement of these hypnotic drugs. [4][5][6][7] At present Propofol is the most frequently investigated hypnotic drug and have been proved to follow the same hypothesis of higher the anxiety, higher the amount of drug required. 5,8 But some recent studies have come with different results.…”

Section: Introductionmentioning

confidence: 99%

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Effect of pre-anesthetic anxiety and heart rate on propofol dose requirement for induction: A correlation study

Hazra

Das

et al. 2017

Asian J Med Sci

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Background: Though anxiety is associated with increase in heart rate and cardiac output, there is conflicting reports regarding its effect on propofol induction dose. Aims and Objectives: The aim of the study was to delineate the correlation between pre-anesthetic anxiety and heart rate on propofol requirement for induction. Materials and Methods: Total 42 patients of ASA (American Society of Anesthesiologists) physical status I and II, 13 male and 29 female, aged between 18 to 50 years and scheduled for elective surgery under general anesthesia, were enrolled in this study. Trait anxiety in the waiting room and state anxiety both in the waiting room and operating room were assessed using Spielberger's revised State-Trait Anxiety Inventory (STAI) scale. After heart rate (HR) recording, anesthesia was induced with 200 ml/hr 1% propofol infusion till loss of verbal contact. Results: Pre-anesthetic trait anxiety and HR had strong positive correlation with propofol requirement (ρ>0.6, P<0.05) while state anxiety had not. But pre-anesthetic state anxiety measured just before induction is strongly associated with increase in HR (ρ>0.6, P<0.05).Conclusion: Pre-operative anxiety should be considered and the dose of propofol should be titrated for induction accordingly. Further, larger trials with more sophisticated monitoring are needed to confirm our findings.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effect of pre-anesthetic anxiety and heart rate on propofol dose requirement for induction: A correlation study

Hazra

Das

et al. 2017

Asian J Med Sci

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“…5 Preoperative anxiety and pain sensitivity have been shown to be independent predictors of propofol and sevoflurane requirements in general anesthesia as well as risk factors for poor pain control in the postoperative period. 6 The most important predictor of postoperative pain in ambulatory surgery is the presence of preoperative pain. Other factors that may also impact anesthesiologists' care include the anticipated degree of postoperative pain and the patient's high preoperative expectations regarding postoperative analgesia.…”

Section: Preoperative Pain Anxiety and Catastrophizingmentioning

confidence: 99%

“…5 Il a été démontré que l'anxiété préopératoire et la sensibilité à la douleur étaient des prédicteurs indépendants de besoins élevés en propofol et en sévoflurane durant l'anesthésie générale et constituaient des facteurs de risque de mauvais soulagement de la douleur en période postopératoire. 6 Le prédicteur le plus important de douleur postopératoire en chirurgie ambulatoire est la présence de douleur préopératoire. Parmi les autres facteurs pouvant également influencer les soins des anesthésiologistes, citons le degré anticipé de douleur postopératoire et les attentes préopératoires élevées du patient concernant l'analgésie postopératoire.…”

Section: Douleur Préopératoire Anxiété Et Catastrophisationunclassified

Why anesthesiologists need to care about the way chronic pain is managed

Clark

Spanswick

2013

Can J Anesth/J Can Anesth

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Psychological correlates of acute postsurgical pain: A systematic review and meta‐analysis

Sobol-Kwapińska

Bąbel

Płotek

et al. 2016

European Journal of Pain

117

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Due to the frequency of surgeries, acute postsurgical pain (APSP) is a common problem. However, the role of psychological factors in the experience of this kind of pain has not been well established. In this review, we focused on presurgical psychological factors associated with the experience of APSP. A systematic search of articles was performed using PsycARTICLES, PsycINFO, PubMed, MEDLINE, Scopus, Cochrane and DARE. For each study, we assessed the risk of bias, the level of evidence, the corresponding score points and the degree of association with APSP. Separate meta-analyses were performed for the selected variables. Fifty-three relevant publications were selected. Pain catastrophizing, optimism, expectation of pain, neuroticism, anxiety (state and trait), negative affect and depression were classified as likely associated with APSP. Only one of the analysed psychological variables - locus of control - was recognized as shown unlikely association with APSP. Results of meta-analyses suggested that pain catastrophizing was most strongly linked with APSP. Results of the studies reviewed suggest that patients who do not exaggerate the negative aspects of the situation and who have positive expectation of the future before undergoing surgery report lower levels of APSP than patients who catastrophize pain and expect negative events in the future. An increasing interest in preoperative positive psychological variables has been observed over the last few years in studies of surgical patients. WHAT DOES THIS REVIEW ADD?: Pain catastrophizing, optimism, expectation of pain, neuroticism, anxiety (state and trait), negative affect and depression were classified as likely associated with acute postsurgical pain, and locus of control was classified as unlikely associated with acute postsurgical pain. Anxiety was the psychological variable most frequently measured before surgery. Pain catastrophizing was most strongly linked with acute postsurgical pain.

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Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia

Abstract: Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia. Anaesthetic and analgesic doses could be modified based on the patient's preoperative anxiety and pain sensitivity.

Cited by 133 publications

References 28 publications

Effect of pre-anesthetic anxiety and heart rate on propofol dose requirement for induction: A correlation study

Effect of pre-anesthetic anxiety and heart rate on propofol dose requirement for induction: A correlation study

Why anesthesiologists need to care about the way chronic pain is managed

Psychological correlates of acute postsurgical pain: A systematic review and meta‐analysis

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