Prenatal evaluation and postnatal early outcomes of fetal ventriculomegaly

Tugcu, Ali Ulas; Gülümser, Çağrı; Ecevit, Ayşe; Abbasoğlu, Aysel; Uysal, Nihal Şahin; Kupana, Ebru Sebnem; Yanik, Fatma Filiz; Tarcan, Aylin

doi:10.1016/j.ejpn.2014.07.002

Cited by 22 publications

(18 citation statements)

References 20 publications

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“…Signorelli et al (3) reported 60 cases of mild ventriculomegaly, and none had poor prognoses; thus, the researchers concluded that mild ventriculomegaly was a variation, and subsequent studies have supported this conclusion (25,26). However, Kutuk et al (12) reported that 9 out of 25 cases with mild VM showed mental or locomotor activity retardation, and some studies have supported these findings (11,(27)(28)(29).…”

Section: Discussionmentioning

confidence: 71%

Fetal ventriculomegaly: Pregnancy outcomes and follow-ups in ten years

Chu

Zhang

Yan

et al. 2016

BST

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Section: Discussionmentioning

confidence: 71%

Fetal ventriculomegaly: Pregnancy outcomes and follow-ups in ten years

Chu

Zhang

Yan

et al. 2016

BST

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“…However, evaluation of the ventricular system by ultrasound may be affected by a number of factors such as skull ossification, fetal location, abnormal microstructure or transposition, rotation of the brain, and technical skill of the operator, all of which can increase the chances of missed diagnosis or misdiagnosis. Some studies have reported that the missed diagnosis rate of associated developmental abnormalities at the first diagnosis of is 12.8% . Magnetic resonance imaging (MRI) offers good soft‐tissue contrast, high‐spatial resolution, and a wide imaging field.…”

Section: Introductionmentioning

confidence: 99%

Prognosis of fetuses with ventriculomegaly: An observational retrospective study

et al. 2019

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Objective To investigate the prognosis of fetuses with ventriculomegaly (VM). Methods Clinical data were collected from 234 cases of fetal VM diagnosed by ultrasound between March 2010 and July 2016. VM progression was monitored, and karyotyping and infection screening performed. Magnetic resonance imaging (MRI) was performed where increasing ventricular diameter was noted. Neonatal behavioral neurological assessment (NBNA) was carried out after birth, and Bayley Scales of Infant Development assessment at 6 months. Results The in utero outcomes of Group A were better than Group B in 173 pregnancies. Isolated VM (IVM) was associated with better prognosis than nonisolated VM (NIVM); the regression rates were 74.6% (59/79) and 52.1% (49/94), respectively (χ2 = 10.222, .006). The NBNA scores were significantly higher in Group A than Group B (χ2 = 4.231, .004), but not significantly different between IVM and NIVM. The composition ratios of both the psychomotor and mental developmental index (PDI and MDI) scores were not significantly different between Groups A and B (Z = 1.869, .062 and Z = 0.826, .409, respectively). Significant differences in in utero outcomes were observed between IVM and NIVM cases in Groups A and B. Conclusions Fetal VM prognosis is affected by the width of ventricle, chromosome abnormalities, coexisted abnormalities, and in utero progression.

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“…While isolated VM can be compatible with normal neurodevelopment, hydrocephalus in association with other anomalies leads to a less favorable prognosis, and fetal MR can be additive in characterizing underlying parenchymal malformations . Gaglioti et al report that the neurodevelopmental outcome of isolated VM is most often normal when mild (ventricular width between 10 and 12 mm), while the rates of associated malformations, chromosomal anomalies, and infection are higher with moderate or severe VM, leading to less favorable outcomes .…”

Section: Discussionmentioning

confidence: 99%

Clinical outcomes following prenatal diagnosis of asymmetric ventriculomegaly, interhemispheric cyst, and callosal dysgenesis (AVID)

Gibson

Pinter³

et al. 2018

Prenatal Diagnosis

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What's already known about this topic? Fetal ventriculomegaly can be isolated or be a component of structural brain anomaly. Prenatal counseling can be challenging given the variable clinical outcomes associated with fetal ventriculomegaly. When fetal ventriculomegaly is associated with a structural anomaly such as a callosal malformation, postnatal outcomes are worse than for isolated ventriculomegaly. What does this study add? When severe asymmetric ventriculomegaly is identified, an underlying callosal anomaly and midline interhemispheric cyst can be present (AVID triad). Prenatal diagnosis of the AVID triad leads to progressive severe macrocephaly in utero, which often leads to cesarean section delivery. All children in our series with prenatally diagnosed AVID required at least one and in general several neurosurgical procedures, including CSF shunting in all cases. Most of these children had at least moderate to severe motor and language delays, with a wide range of visual deficits, craniofacial abnormalities, and medical comorbidities.

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Prenatal evaluation and postnatal early outcomes of fetal ventriculomegaly

Cited by 22 publications

References 20 publications

Fetal ventriculomegaly: Pregnancy outcomes and follow-ups in ten years

Fetal ventriculomegaly: Pregnancy outcomes and follow-ups in ten years

Prognosis of fetuses with ventriculomegaly: An observational retrospective study

Clinical outcomes following prenatal diagnosis of asymmetric ventriculomegaly, interhemispheric cyst, and callosal dysgenesis (AVID)

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