“…With the progress made in early ultrasound assessment of the pregnancy, nowadays the BSA is being diagnosed in the first trimester. Since 2000, when the first case of BSA was diagnosed at 9+5 weeks (22) , the literature reports of cases discovered in early first trimester increased (3,5,21,23,25,27) . Using the nuchal translucency as maker for first trimester anomalies, we found a 2009 and two 2011 studies stating the importance of first trimester screening in early detection of BSA (5,28,29) .…”