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What's already known about this topic? Cases of early pregnancy diagnosis of body stalk anomaly are relatively few, particularly in twins. What does this study add? This is the first diagnosis of concordant body stalk anomaly in monoamniotic twins before 10 gestational weeks. The observation of an intact amniotic cavity with both embryos showing the same anomaly supports a primary ectodermal failure as the cause for body stalk anomaly.

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Poster abstracts newborn, umbilical artery power Doppler with zero or reverse enddiastolic blood flow (blood flow class IIIa/IIIb) or changes in venous duct blood flow. We collected data about pregnancy, prenatal ultrasound examinations and result of pregnancy. Results: 20 pregnancies were included. All women underwent caesarian section. Indication was severe maternal complication, worsening of power Doppler or deterioration of the fetus. 4 children died in postnatal period, 3 have some birth defects. Mean time of first ultrasound was 29+2g.w.11 fetuses had zero flow and 6 had reverse enddiastolic blood flow in umbilical artery. Mean estimated body weight was on 4.1 th centile, mean pulsatile index in umbilical artery 2.39 (SD0.32) and cerebroplacental ratio 0.65 (SD0.18). Mean gestation week at delivery 29+5g.w, fetal body weight 891 g, Apgar score at 5 th min 8, 10 th min 9, arterial pH7.25 (SD1.69) and venous pH7.3 (SD1.63). Conclusions: Management of perinatal care of early onset IUGR with signs of blood flow redistribution is based on values of pulsatile index of umbilical artery, medial cerebral artery, venous duct and its pattern. Extreme or severe prematurity and maternal hypertensive complication are important factors.

was to determine the performance of screening for PE in singleton pregnancies during routine clinical practice. Methods: Between 2011-2012 measurements of UtA-PI were performed at 11-13+6 weeks, and mean pulsatility index (PI) was calculated. Doppler, maternal history and biometry variables (age, ethnic origin, method of conception, BMI, parity, smoking, family or personal history of hypertension or PE, blood pressure) were combined with first trimester PAPP-A to assess the risk of PE. Astraia Software 2.3.2 was used in risk calculation. Results: 2552 women were recruited after informed consent to the study, and outcome data were available in 950 (37.2%) cases. PE occurred in 36 (3.8%) patients. The overall detection rate of early and late PE was 44.4% (16/36) with a false positive rate (FPR) of 12.3% (112/914). There were only 2 cases with early PE, the detection rate was 50% (1/2), with a FPR of 18.7% (178/948). The detection rate of the late PE (delivery at 34 th weeks or after) was 44.1% (15/34), with a FPR of 9.5% (87/914). Conclusions: Combining risk factors in the mother's history with UtA-PI allows calculation of patient-specific risk for the development of PE. Because of the small number of early PE cases in our study population our detection rate can not be taken into consideration. The detection rate (44%) of late PE in our study is comparable with the published retrospective data (60%). The Astraia software used only serum PAPP-A for risk calculation. Further biochemical markers might improve the detection rate. Follow-up of our recruited cases is still going on.