Prenatal and postnatal factors increase risk of severe ROP

Anaya-Alaminos, Roberto; García-Serrano, J.L.; Cantero-Hinojosa, J.

doi:10.3109/14767058.2013.818648

Cited by 5 publications

(4 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[24] Low serum IGF-1 levels in premature infants in the postnatal period are known to increase the risk and severity of ROP. [2526] Anaya-Alaminos et al [13] demonstrated that advanced stage ROP was statistically higher in the lower BW twins than their larger-sized siblings. They showed that the nonvascularized area of the temporal retina was significantly larger in the lower BW group at the first ROP examination.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of birth weight on retinopathy of prematurity in discordant twin pairs

Petriçli

Kara

Işık

et al. 2019

Indian J Ophthalmol

View full text Add to dashboard Cite

Purpose: Since twin pairs with discordance have equal gestational age (GA), discordant twins may constitute an appropriate group to investigate the specific effect that birth weight (BW) has on the development of retinopathy of prematurity (ROP). The present study aims to investigate the effect of BW on any and severe stages of ROP development in twin pairs. Methods: Fifty-two discordant twin pairs (104 preterms) born ≤32 gestational weeks, who were diagnosed with a minimum of 18% discordance between their BWs, were retrospectively analyzed. Twin pairs were separated into two groups based on the BW of each pair. The rate of any stage of ROP, Type 1 ROP, and perinatal risk factors were compared statistically among twin pairs. Results: The rate of any stage of ROP and Type 1 ROP was 24.0% and 4.8% in the whole group, respectively. A statistically significant difference was shown between lower and higher BW groups at any stage of ROP development (34.6% vs. 13.4%, P = 0.02). However, no difference was observed in Type 1 ROP development (7.7% vs. 1.9%, P = 0.17). No significant differences were found between twin pairs regarding neonatal morbidities. The number of small GA (SGA) infants in the smaller twin group was statistically higher than larger group and regression analysis showed that being SGA had significant correlation with any stage of ROP (odds ratio: 4.98, P = 0.02). Conclusion: This study showed that BW serves an effective role at any stage of ROP development in discordant twin pairs; however, no significant difference in terms of Type 1 ROP.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The results of studies about the relationship between inter-twin BW discordance and ROP are contradictory. [13141516] One reason for this is that BW discordance rates in these studies are different.…”

mentioning

confidence: 99%

Effect of birth weight on retinopathy of prematurity in discordant twin pairs

Petriçli

Kara

Işık

et al. 2019

Indian J Ophthalmol

View full text Add to dashboard Cite

show abstract

“…Premature infants suffer from delayed retinal vascular development. The delayed retinal vascular development together with other risk factors such as intubation days, BPD ≥ 3, low weight gain at 4-6 weeks, avascular temporal retinal area, very low gestational age, performance of transfusions, sepsis, apnea at birth, PDA, and days of CPAP therapy increases the risk of suffering from severe ROP [13].…”

Section: Discussionmentioning

confidence: 99%

Speed of Retinal Vascularization in Retinopathy of Prematurity: Risk and Protective Factors

Larraya

Molina

Fernández

et al. 2019

BioMed Research International

View full text Add to dashboard Cite

Objective. The objective was to study the risk and protective factors involved in retinal vascular development of preterm infants with retinopathy of prematurity. Methods. Between 2000 and 2017, 185 preterm infants were included in the protocol for retinopathy of prematurity. Risk factors associated with speed of retinal vascularization <0.5 disc diameter/week were studied in each of them. Results. The statistically significant variables related to retinal vascular development <0.5 DD/w were intubation days, degree 3 of bronchopulmonary dysplasia, weight gain at 4-6 weeks, avascular temporal area, gestational age, number of transfusions, sepsis, number of risk factors, apnea at birth, presence of ductus arteriosus, and days of continuous positive airway pressure therapy. After the multivariate logistic regression analysis, only three variables were found to be significant: intubation days (p=0.005), degree 3 of bronchopulmonary dysplasia (p=0.022), and weight gain at 4–6 weeks (p=0.031). Conclusion. In retinopathy of prematurity, degree 3 of bronchopulmonary dysplasia and intubation days cause delayed retinal vascular development, whereas greater postnatal weight gain favors an appropriate rate of retinal vascularization.

show abstract

“…Furthermore, premature twins with a smaller area of vascularized retina have a higher risk of severe ROP (30).…”

Section: Discussionmentioning

confidence: 99%

Risk Factors of Retinopathy of Prematurity Associated with Delayed Retinal Vascular Development

et al. 2017

View full text Add to dashboard Cite

Objectives: To assess risk factors of retinopathy of prematurity leading to delayed retinal vascularization in the first stage of ROP. Methods:A retrospective study (2000 -2016) was performed in 275 infants who were born at a gestational age of ≤ 32 weeks. Delayed vascular development was calculated as the difference in avascular area measured in terms of disc diameters between patients with risk factor and those with no risk factor. Results:Intrauterine fetal demise of one twin, apnea, exchange tranfusion and intubation days (≥ 10 days) lead to delayed retinal vascularization of 1.74, 1.58, 1.17, and 1.11 disc diameters and of 3.35, 3.04, 2.25 and 2.13 weeks respectively. Delayed retinal vascular development was less than 1 disc diameter in other factors such as HS-PDA, sepsis, degree of hyaline membrane ≥ III, cerebral hemorrhage, birth weight (every 100 g less), gestational age (every week less), postnatal weight gain (every 1 g less/day) and cerebral hemorrhage. However, since these factors are quantitative (birth weight, gestational age and postnatal weight gain), the greater the adverse effect, the greater the delay will be. Conclusions:Intrauterine fetal demise of one twin, apnea, exchange tranfusion and intubation days (≥ 10 days) lead to delayed retinal vascular development more than 1 disc diameter at 4 -6 weeks of postnatal life.

show abstract

Prenatal and postnatal factors increase risk of severe ROP

Cited by 5 publications

References 2 publications

Effect of birth weight on retinopathy of prematurity in discordant twin pairs

Effect of birth weight on retinopathy of prematurity in discordant twin pairs

Speed of Retinal Vascularization in Retinopathy of Prematurity: Risk and Protective Factors

Risk Factors of Retinopathy of Prematurity Associated with Delayed Retinal Vascular Development

Contact Info

Product

Resources

About