Premature familial sebaceous hyperplasia: Successful response to oral isotretinoin in three patients

Grimalt, Ramón; Ferrando, Juan; Mascaró, José M.

doi:10.1016/s0190-9622(97)70082-3

Cited by 37 publications

(34 citation statements)

References 2 publications

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“…Some success has been reported with these treatments, but some of these procedures can result in scarring in some individuals, and recurrence or development of further lesions is frequent. A case series reported the successful response to oral isotretinoin in three patients with marked improvement in skin texture and a reduction in the size of the lesions [6]. Two out of the three patients in the case report were found to be doing well after the discontinuation of the oral treatment, but they continued with isotretinoin gel 0.05% [6].…”

Section: Treatmentmentioning

confidence: 96%

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Sebaceous hyperplasia

Hogan

Mohammad

2011

Expert Review of Dermatology

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Section: Treatmentmentioning

confidence: 96%

“…Sebaceous hyperplasia occurrence on the mouth, chest, areola, shaft of penis and vulva has been reported [1, 2,5]. Treatment is usually justified on the basis of cosmetic appearance with electrosurgery, laser treatments, photodynamic therapy and, in the most severe cases, isotretinoin [6][7][8].…”

mentioning

confidence: 99%

Sebaceous hyperplasia

Hogan

Mohammad

2011

Expert Review of Dermatology

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“…Other procedures that have also been used include excision, electrocauterization, cryotherapy, shaving, curettage and cauterization with chemical agents used topically, although there is a risk of depigmentation or scarring with these latter options. [16][17][18][19][20][21][22][23][24][25] Many laboratory studies have shown the effect of androgens on the sebaceous glands. A review of the literature on several research models confirmed the effect of androgens in triggering the activity of the sebaceous glands and indicated which of these hormones may be implicated in triggering these glands.…”

Section: Introductionmentioning

confidence: 99%

Hiperplasia sebácea cutânea: estudo piloto para a correlação da doença com hormônios androgênios

Tagliolatto¹,

Alchorne

Enokihara

2011

An. Bras. Dermatol.

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FUNDAMENTOS: As glândulas sebáceas são suscetíveis à ação dos hormônios androgênios e apresentam proliferação benigna com a idade, ou seja, hiperplasia. OBJETIVOS: Estudo piloto para verificar se há correlação entre a taxa de hormônios masculinos circulantes e o aumento da incidência da hiperplasia das glândulas sebáceas. MÉTODOS: 16 pacientes do sexo feminino, com diagnóstico de hiperplasia sebácea cutânea, foram comparados a um grupo-controle de mesmo gênero e idades semelhantes, sem a doença. Ambos os grupos foram submetidos a testes de dosagem sanguínea para avaliação das taxas de hormônios androgênios circulantes (testosterona livre e total, androstenediona). Os resultados foram tabulados e analisados estatisticamente. RESULTADOS: Os dados demonstraram não haver mudanças nos níveis de hormônios masculinos circulantes dos pacientes com hiperplasia sebácea cutânea, quando comparados ao grupo-controle. CONCLUSÃO: Os dados sugerem que não há alterações estatisticamente significantes nas taxas dos hormônios circulantes (testosterona livre e total, androstenediona, deidroepiandrosterona, sulfato de deidroepiandrosterona) dos pacientes com hiperplasia sebácea cutânea.

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“…Although it is a completely benign lesion and does not require treatment, it can sometimes be cosmetically disturbing or clinically resemble BCC; therefore, a biopsy might be necessary in some cases. Therapy consists of photodynamic therapy, topical trichloroacetic acid, laser treatment (pulsed-dye or CO 2 laser), electrosurgery, shave excision, excision or oral isotretinoin therapy for multiple widespread disfiguring sebaceous hyperplasia [41-46]. …”

Section: Non-malignant Tumors Of the Nosementioning

confidence: 99%

Cutaneous lesions of the nose

Sand

Thrandorf

et al. 2010

Head Face Med

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Skin diseases on the nose are seen in a variety of medical disciplines. Dermatologists, otorhinolaryngologists, general practitioners and general plastic and dermatologic surgeons are regularly consulted regarding cutaneous lesions on the nose. This article is the second part of a review series dealing with cutaneous lesions on the head and face, which are frequently seen in daily practice by a dermatologic surgeon. In this review, we focus on those skin diseases on the nose where surgery or laser therapy is considered a possible treatment option or that can be surgically evaluated.

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Premature familial sebaceous hyperplasia: Successful response to oral isotretinoin in three patients

Cited by 37 publications

References 2 publications

Sebaceous hyperplasia

Sebaceous hyperplasia

Hiperplasia sebácea cutânea: estudo piloto para a correlação da doença com hormônios androgênios

Cutaneous lesions of the nose

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