Preliminary Study on HA Coating Percutaneously Implanted in Bone

Yang, Biwei; Weng, Jie; Xd, Li; Yang, Zhuang; Jm, Feng; Chen, Jy; Xd, Zhang

doi:10.1177/039139889902201010

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…There remain major problems: one, how to consistently create an infection-free seal of skin around the pylon [3–7]. The quality of the pylon-bone interface is also an issue that must be investigated further.…”

Section: Introductionmentioning

confidence: 99%

New method of fixation of in-bone implanted prosthesis

Pitkin

Cassidy²,

Muppavarapu³

et al. 2013

JRRD

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This article presents results on the effectiveness of a new version of the titanium porous composite skin and bone integrated pylon (SBIP). The SBIP is designed for direct skeletal attachment of limb prostheses and was evaluated in a pre-clinical study with three rabbits. In accordance with the study protocol, a new version of the pylon (SBIP-3) was implanted into the hind leg residuum of three rabbits. The SBIP-3 has side fins that are designed to improve the bond between the bone and pylon. The fins are positioned inside two slots precut in the bone walls; their length can be adjusted to match the thickness of the bone walls. After 13 (animal 1) or 26 wk (animals 2 and 3), the animals were sacrificed and samples collected for histopathological analysis. The space between the fins and the bone into which they were fit was filled with fibro-vascular tissue and woven bone. No substantial inflammation was found. We suggest that if further studies substantiate the present results, the proposed method can become an alternative to the established technique of implanting prostheses into the medullar canal of the hosting bone.

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Section: Introductionmentioning

confidence: 99%

New method of fixation of in-bone implanted prosthesis

Pitkin

Cassidy²,

Muppavarapu³

et al. 2013

JRRD

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The Influence of Surface Bioactivated Modification on Titanium Percutaneous Implants Anchored in Bone

Yang

Deng

et al. 2006

Int J Artif Organs

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In order to achieve biological sealing and resist mechanical damage of load-bearing percutaneous devices, Ti with excellent mechanical properties was anodic-oxidized to be endowed with bioactivity, with plasma-sprayed hydroxyapatite coated Ti as control. Similar to previous works, hydroxyapatite coating could bond tightly with living tissues, resulting in implant stability for whole implantation periods. Meanwhile, when anodic-oxidized bioactivated Ti was implanted percutaneously in vivo, it could induce a layer of calcium phosphate at the interface of tissues/implant. This layer of Ca-P not only induced the fibrous tissue or collagen ingrowth in its structure, but also improved the osteointegration between the bone and the implant. There was no significant biological response difference for the anodic-oxidized Ti and HA coated Ti at different implantation period with histological statistical analysis (p>0.05). Accordingly, suitable bioactivated modified surface of Ti by anodic-oxidized method could not only obtain the same results as the HA coating, but also might avoid some drawbacks of plasma-sprayed HA coatings to achieve biological sealing for a long period in vivo.

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Preliminary Study on HA Coating Percutaneously Implanted in Bone

Cited by 2 publications

References 8 publications

New method of fixation of in-bone implanted prosthesis

New method of fixation of in-bone implanted prosthesis

The Influence of Surface Bioactivated Modification on Titanium Percutaneous Implants Anchored in Bone

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