Preliminary Study of the Antimicrobial, Anticoagulant, Antioxidant, Cytotoxic, and Anti-Inflammatory Activity of Five Selected Plants with Therapeutic Application in Dentistry

Villarreal, Sonia Martha López; Elizondo-Luévano, Joel H.; Pérez-Hernández, Raymundo Alejandro; Sánchez, Eduardo Sánchez; Star, María J. Verde; Ríos, Rocío Castro; Garza-Tapia, Marsela; Luis, Osvelia Esmeralda Rodríguez; Chávez-Montes, Abelardo

doi:10.3390/ijerph19137927

Cited by 8 publications

(1 citation statement)

References 58 publications

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“…Natural products like pineapples(bromelain) possess effective antioxidant and antimicrobial properties and are safe exhibiting fewer side effects. 12,13,14 On analyzing plaque and gingival index, bromelain mouth rinse have less plaque and gingival score on comparing with placebo for a period of 1 month, which is in accordance with previous studies. The gingival index scores were statistically significant as compared to the placebo group.…”

Section: Resultssupporting

confidence: 88%

Effectiveness of Bromelain Mouthrinse in Gingival Inflammation and Bacterial Plaque Among Adolescents: A Randomized Clinical Trial

Patel

Kumaresan

2022

IJCD

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Background: Mouthwashes are adjunct to regular brushing and flossing. Chlorhexidine is considered as a gold standard among mouth rinses. However, the most commonly known side effects include discolouration of teeth and the tongue particularly on the dorsum part. Hence the study was conducted to evaluate the effectiveness of Bromelain mouth rinse in gingival inflammation and bacterial plaque among adolescents. Methods and methodology: This double-blinded, randomized controlled trial was conducted in accordance with Consolidated Standards of reporting Trials (CONSORT) in Public Health Dentistry Department at Saveetha University. The protocol was approved by the Institutional Review Board (IRB). 30 patients with moderate gingivitis were included in the study. All subjects signed an IRB-approved consent form. Participants from 15 to 19 years are recruited from the Urban health programmes through dental camps. Results: No attempt was made for oral prophylaxis before the commencement of the study. The severity of gingivitis and plaque accumulation were assessed by gingival and plaque indices. Gingival index (Löe and Silness, 1963) and plaque index (Löe, 1967) were measured initially at baseline The trial was followed up for 30 days. The participants were instructed to rinse with plain water thoroughly. They were then directed to spit into a sterile plastic container after 5 minutes.At baseline, there was no significant difference in GI and PI scores among the groups (P=0.78 and 0.62) respectively. At one month follow up, there was significant difference in the mean GI and PI scores (P=0.02 and P=0.01) respectively. Conclusion: Bromelain mouthwash is beneficial in improving gingival status due to its profound styptic action, with sufficient reduction in plaque scores without any adverse effects.

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Section: Resultssupporting

confidence: 88%