Genus Equisetum L: Taxonomy, toxicology, phytochemistry and pharmacology

Sureshkumar, Jeyalatchagan; Jenipher, Christopher; Sriramavaratharajan, Venkatraman; Gurav, Shailendra; Gandhi, Gopalsamy Rajiv; Ravichandran, K.; Ayyanar, Muniappan

doi:10.1016/j.jep.2023.116630

Cited by 4 publications

(1 citation statement)

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“…In this study, AgNPs were derived from the plant Equisetum telmateia via green synthesis. E. telmateia, commonly known as horsetail, belongs to the Equisetaceae family, and it is renowned for its traditional use in treating urinary system diseases, stomach pain, eczema, and mouth infections [14]. The plant is rich in biologically active compounds, and the existing literature highlights its antioxidant and antimicrobial effects.…”

Section: Introductionmentioning

confidence: 99%

Ibuprofen-Loaded Silver Nanoparticle-Doped PVA Gels: Green Synthesis, In Vitro Cytotoxicity, and Antibacterial Analyses

Altınay,

Köse,

Ateş

et al. 2024

Gels

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In contrast to conventional drug delivery systems, controlled drug release systems employ distinct methodologies. These systems facilitate the release of active substances in predetermined quantities and for specified durations. Polymer hydrogels have gained prominence in controlled drug delivery because of their unique swelling–shrinkage behavior and ability to regulate drug release. In this investigation, films with a hydrogel structure were crafted using polyvinyl alcohol, a biocompatible polymer, and silver nanoparticles. Following characterization, ibuprofen was loaded into the hydrogels to evaluate their drug release capacity. The particle sizes of silver nanoparticles synthesized using a green approach were determined. This study comprehensively examined the structural properties, morphological features, mechanical strength, and cumulative release patterns of the prepared films. In vitro cytotoxicity analysis was employed to assess the cell viability of drug-loaded hydrogel films, and their antibacterial effects were examined. The results indicated that hydrogel films containing 5% and 10% polyvinyl alcohol released 89% and 97% of the loaded drug, respectively, by day 14. The release kinetics fits the Korsmeyer–Peppas model. This study, which describes nanoparticle-enhanced polyvinyl alcohol hydrogel systems prepared through a cost-effective and environmentally friendly approach, is anticipated to contribute to the existing literature and serve as a foundational study for future research.

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Section: Introductionmentioning

confidence: 99%