Preliminary studies on eicosanoid production by fish leucocytes, using GC‐mass spectrometry

Rowley, Andrew F.; Barrow, Susan E.; Hunt, T. C.

doi:10.1111/j.1095-8649.1987.tb05301.x

Cited by 22 publications

(6 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ankley et al (1989) demonstrated that lipids affect the activity of membrane-associated hepatic enzymes involved with xenobiotic metabolism in channel catfish. In addition, eicosanoids are produced by fish leukocytes using enzymatic pathways similar to those in mammals (Rowley et al 1987;Pettitt and Rowley 1990); however, the roles of prostaglandins and leukotrienes in immune modulation and inflammation have not been determined for fish.…”

Section: Discussionmentioning

confidence: 99%

Influence of Dietary Lipid and Temperature on Bactericidal Activity of Channel Catfish Macrophages

Sheldon

Blazer

1991

Journal of Aquatic Animal Health

View full text Add to dashboard Cite

We fed juvenile channel catfish Ictalurus punctatus purified diets containing different lipid sources for 90-110 d to examine the influence of dietary lipids on intracellular killing of Edwardsiella ictaluri by pronephros macrophages. The diets contained either menhaden oil, soybean oil, beef tallow, or a combination of all three lipids. We performed the study with nonimmune and immunized fish acclimated to optimal (28°C) and suboptimal (19°C) temperatures. In both temperature trials, bactericidal activity was positively correlated with the level of n-3 fatty acids in the diet (particularly long-chain highly unsaturated fatty acids). Vaccination resulted in substantially enhanced bactericidal activity, except at suboptimal temperature in fish fed the diet containing beef tallow (primarily saturated and monoenoic fatty acids). Overall results were similar at optimal and suboptimal temperatures. This study demonstrates the potential for nutritional manipulation of disease resistance in fish and illustrates the need for standardized diets in fish health research.

show abstract

Section: Discussionmentioning

confidence: 99%

Influence of Dietary Lipid and Temperature on Bactericidal Activity of Channel Catfish Macrophages

Sheldon

Blazer

1991

Journal of Aquatic Animal Health

View full text Add to dashboard Cite

show abstract

“…Although there is very little information available on these soluble mediators in fish, preliminary evidence indicates that all groups are produced by fish leukocytes (Rowley et al 1987). In mammals, FA composition of cell membranes is primarily altered by diet.…”

Section: Nutritional Effects On Macrophage Functionmentioning

confidence: 99%

Piscine Macrophage Function and Nutritional Influences: A Review

Blazer

1991

Journal of Aquatic Animal Health

103

View full text Add to dashboard Cite

Macrophage function is an important factor in resistance to infectious diseases in fish. Macrophages are the principal phagocytic cells and play an integral role in the specific immune response. Several factors, including nutrition and environmental stress, are known to affect macrophage function. In economically important cultured fish, the potential for enhancing macrophage function through dietary manipulation is especially attractive. This paper reviews the functions of macrophages, methodologies for their collection, assays to study various functions, and the influences of various nutritional factors on macrophage function. Macrophage Function in FishFish, like other vertebrates, respond to infectious agents in both specific and nonspecific manners. Specific mechanisms are generally regarded as the immune response. Fish appear to have most of the same cellular and humoral immune components as warm-blooded vertebrates. Perhaps the most significant difference is the temperature dependence of certain aspects of the immune response (Cuchens and Clem 1977;Avtalion 1981). In addition, the magnitude of the piscine response is often smaller, and the peak primary or secondary response is often delayed when compared with that of mammalian species.The first and often most important responses of fish to infectious agents are nonspecific. These include the soluble and cellular factors of acute in-

show abstract

“…Leucocytes of the dogfish Scyliorhinus canicula Linnaeus, 1758 secerned high levels of PGE 2 , PGD 2 and PGF 2α (Figure 5b) when exposed to the Ca 2+ ionophore A23187 [78]. PGE 2 and PGF 2α were found in the red blood cells of the toadfish Opsanus tau Linnaeus, 1766 [79] (Figure 5a).…”

Section: Prostaglandins and Derivative Molecules In Marine Organismsmentioning

confidence: 99%

“…Rowley et al [78] tested the ability of leucocytes extracted from the blood of the dogfish Scyliorhinus canicula (Figure 5b) to produce and release PGs and TXs during their degranulation induced by the calcium ionophore A23187. While PGF 2α , PGE 2 , and PGD 2 levels were always high after the stimulus, the levels of TXB 2 were low and detectable in the supernatant only 5 min after the start of the stimulus, with levels increasing after 10 and 15 min [78].…”

Section: Marine Thromboxanementioning

confidence: 99%

Prostaglandins in Marine Organisms: A Review

et al. 2019

View full text Add to dashboard Cite

Prostaglandins (PGs) are lipid mediators belonging to the eicosanoid family. PGs were first discovered in mammals where they are key players in a great variety of physiological and pathological processes, for instance muscle and blood vessel tone regulation, inflammation, signaling, hemostasis, reproduction, and sleep-wake regulation. These molecules have successively been discovered in lower organisms, including marine invertebrates in which they play similar roles to those in mammals, being involved in the control of oogenesis and spermatogenesis, ion transport, and defense. Prostaglandins have also been found in some marine macroalgae of the genera Gracilaria and Laminaria and very recently the PGs pathway has been identified for the first time in some species of marine microalgae. In this review we report on the occurrence of prostaglandins in the marine environment and discuss the anti-inflammatory role of these molecules.

show abstract

Preliminary studies on eicosanoid production by fish leucocytes, using GC‐mass spectrometry

Cited by 22 publications

References 14 publications

Influence of Dietary Lipid and Temperature on Bactericidal Activity of Channel Catfish Macrophages

Influence of Dietary Lipid and Temperature on Bactericidal Activity of Channel Catfish Macrophages

Piscine Macrophage Function and Nutritional Influences: A Review

Prostaglandins in Marine Organisms: A Review

Contact Info

Product

Resources

About