Preliminary Screening and Phytochemical Profile of Mangifera indica Leave's Extracts, Cultivated in Iraq

Alshammaa, Dhuha

doi:10.20546/ijcmas.2016.509.018

Cited by 6 publications

(6 citation statements)

References 7 publications

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“…Leaf extracts have revealed the presence of all the above said phytochemicals but in case of bark, steroids, cardiac glycosides and saponins were present in few but absent in other varieties. Similar results were obtained by other researchers by analyzing various parts of the plant (Mangifera indica L.) such as in leaf [16] and in bark [24][25][26][27], in leaf and bark [28], in fruits [6], in stem, fruit peel and seed [28]; in stem, leaf, flower and seed kernel [15]. This investigation has also revealed their potentiality in controlling the microbial growth.…”

Section: Discussionsupporting

confidence: 85%

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Phytochemical Screening and Antimicrobial Analysis of Aqueous Extracts of Wild Mango Varieties

Namitha

Jagadeesh

Devaki

2022

JASR

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Phytochemical screening and antibacterial activity of aqueous extracts of bark and leaf of eighteen mango varieties growing in the village Hanavadi, Malavalli taluk, Mandya district, Karnataka state were conducted. They showed the presence of alkaloids, steroids, flavonoids, tannins, cardiac glycosides, saponnins, resins, carbohydrates and proteins. Antibacterial activity tested against six human pathogens- Escherichia coli, Enterobacter aerogenes, Staphylococcus aureus, Streptococcus mutans, Pseudomonas aeruginosa and Bacillus subtilis, by disc diffusion method showed significant inhibition zone against pathogens compared to control. These results disclose the inhibiting property of leaf and bark of wild varieties of mangoes against potential pathogens and thus can be subjected to further investigations for their applications in human phytomedicines.

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Section: Discussionsupporting

confidence: 85%

“…Tests were carried out for detecting alkaloids, flavonoids, carbohydrates, resins [15] steroids, tannins [6] cardiac glycosides, [16] proteins [17] and saponins [18] as per the standard protocols.…”

Section: Phytochemical Testsmentioning

confidence: 99%

Phytochemical Screening and Antimicrobial Analysis of Aqueous Extracts of Wild Mango Varieties

Namitha

Jagadeesh

Devaki

2022

JASR

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“…Previous studies have reported extraction of different chemical compounds such as phenolic acid 6-alkenyl-salicylic acid, anarcardic acid, chlorogenic acid, ellagic acid, betulin, coumaroyl, quercetin, and gallic acid from S. mombin , which exhibited different biological activities including antidiabetic, anti-inflammatory and anti-oxidant effects [ 15 , 21 , 22 , 23 , 24 ]. On the other hand, studies have reported that bioactive compounds identified from M. indica leaves include quercetin and chlorogenic acid which possess anti-oxidant, anti-inflammatory, and antidiabetic activities [ 25 ]. The current study aimed to investigate the in vitro enzyme inhibitory activities and antioxidant properties of the S. mombin and M. indica leaf solvent-partitioned fractions as potential therapeutic sources, which may be helpful in attaining the normoglycemic state in the diabetic condition.…”

Section: Introductionmentioning

confidence: 99%

Inhibitory Effects of Solvent-Partitioned Fractions of Two Nigerian Herbs (Spondias mombin Linn. and Mangifera indica L.) on α-Amylase and α-Glucosidase

et al. 2018

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Therapies directed towards controlling hyperglycemia, the hallmark of type-2 diabetes mellitus, go a long way in managing diabetes and its related complications. Reducing glucose level through the inhibition of the relevant carbohydrate hydrolyzing enzymes is one among many routes in the management of diabetes. This study investigates the in vitro enzyme inhibitory and antioxidant properties of solvent-partitioned fractions of Spondias mombin and Mangifera indica leaves; which are used extensively in the treatment of diabetic patients locally. The leaves of S. mombin and M. indica were extracted with methanol and fractionated to obtain n-hexane (HF), ethyl acetate (EAF), n-butanol (BF), and aqueous (AF) fractions successively. The α-amylase and α-glucosidase inhibitory activities of fractions of S. mombin and M. indica leaves were investigated while the antioxidant activity of each fraction was analyzed using iron chelating and ABTS (2,2’-azino-bis(3-ethylbenzothiazoline)-6-sulphonic acid) radical scavenging assay. Our findings indicated that the ethyl acetate fraction of M. indica leaves contained a considerably higher (p < 0.05) amount of total phenolic, flavonoids, metal ion, and ABTS radical scavenging activity than the ethyl acetate fractions of S. mombin. Furthermore, the ethyl acetate fraction of M. indica had a considerably higher (p < 0.05) inhibitory effect on α-glucosidase (IC50 = 25.11 ± 0.01 μg mL−1), and α-amylase (IC50 = 24.04 ± 0.12 μg mL−1) activities than the S. mombin fraction. Hence, the inhibitory activities of S. mombin and M. indica leaves suggest that they are a potential source of orally active antidiabetic agents and could be employed to formulate new plant-based pharmaceutical and nutraceutical drugs to improve human health.

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“…The filtrate was concentrated using a water bath set at 40 °C. The dried extracts obtained were wrapped in aluminum foil and stored in amber glass containers for further investigations [18,19].…”

Section: Methodsmentioning

confidence: 99%

The In vitro Biological Activity of Biosynthesized Silver Nanoparticles Produced Using Mangifera indica Stem Bark Extract and Properties of Its Pharmaceutical Gel Formulation

2023

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This study reports the production of silver nanoparticles using Mangifera indica stem bark (aqueous and methanol) extracts as capping agents and formulation of pharmaceutical gel loaded with the nanoparticles. The extracts were prepared using standard procedures and utilized in biosynthesizing silver nanoparticles. Biosynthesis was ascertained through colour changes, UV-Visible and FTIR spectroscopy. Antioxidant activity of the extracts and biosynthesized nanoparticles were examined by DPPH method. The antimicrobial evaluation was carried out on Pseudomonas aeruginosa and Staphylococcus aureus. Pharmaceutical gels were produced (F1-F5), and loaded with the nanoparticles. Nanoparticles exhibited maximum absorption under UV-visible spectroscopy between 315 and 320 nm. FTIR spectrum showed that alkene and ester functional groups were conferred on the silver nanoparticles by the extracts used. The nanoparticles demonstrated antimicrobial activity against the organisms, which was significantly higher (p < 0.05) than for extracts and reference drug. The antioxidant capacity was in a concentration-dependent manner but significantly lower (p < 0.05) than that of the reference drug. Formulated gels had acceptable organoleptic profiles, pH range of 6.8-7.1, high viscosity, and pseudoplastic flow patterns. The in vitro release profiles of the gels showed was gradual, with t 90 higher than 2 h. The release seemed to be influenced by the viscosity of the gel systems. In addition, the release kinetics of the nanoparticle-loaded gel systems followed Higuchi model with r 2 ranging from 0.9958 to 0.9980. Mangifera indica extracts were successfully used as bio-reducing agents in the synthesis of silver nanoparticles. The gel formulations had acceptable physical properties and release profiles.

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Preliminary Screening and Phytochemical Profile of Mangifera indica Leave's Extracts, Cultivated in Iraq

Cited by 6 publications

References 7 publications

Phytochemical Screening and Antimicrobial Analysis of Aqueous Extracts of Wild Mango Varieties

Phytochemical Screening and Antimicrobial Analysis of Aqueous Extracts of Wild Mango Varieties

Inhibitory Effects of Solvent-Partitioned Fractions of Two Nigerian Herbs (Spondias mombin Linn. and Mangifera indica L.) on α-Amylase and α-Glucosidase

The In vitro Biological Activity of Biosynthesized Silver Nanoparticles Produced Using Mangifera indica Stem Bark Extract and Properties of Its Pharmaceutical Gel Formulation

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